Ligand Kallidin

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Basic Ligand Information

Molecular Structure
Picture of Kallidin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C56H85N17O12
Kallidin
FYSKZKQBTVLYEQ-FSLKYBNLSA-N
Synonyms:
kallidin-10, KRPPGFSPFR, Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg, Lys-bradykinin, Lys-bradykinin KRPPGFSPFR, Lysyl-bradykinin, Lysylbradykinin

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
kallidin + H2O = Leu + bradykinin
show the reaction diagram
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kallidin + H2O = ?
show the reaction diagram
-
kallidin + H2O = ?
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
low-molecular-weight kininogen + H2O = low-molecular-weight kinin + kallidin
show the reaction diagram
-
-
high molecular weight kininogen + H2O = Met-Lys-bradykinin + Lys-bradykinin + bradykinin + ?
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O = Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe + arginine
show the reaction diagram
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Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O = Lys-Arg-Pro-Pro + Gly-Phe-Ser-Pro-Phe-Arg
show the reaction diagram
-
Lys-bradykinin + H2O = ?
show the reaction diagram
-
Lys-bradykinin + H2O = ?
show the reaction diagram
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Lys-bradykinin KRPPGFSPFR + H2O = ?
show the reaction diagram
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Lys-bradykinin + H2O = ?
show the reaction diagram
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kallidin + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Met-Lys-bradykinin + H2O = Met + Lys-bradykinin
show the reaction diagram
-
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low-molecular-weight kininogen + H2O = low-molecular-weight kinin + kallidin
show the reaction diagram
-
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high molecular weight kininogen + H2O = Met-Lys-bradykinin + Lys-bradykinin + bradykinin + ?
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
human peptide hormone, 10 microM, Arg 4-methylcoumarin 7-amide hydrolysis: 73.7% (wild-type enzyme)
-
competitive against Glu-4-methylcoumaryl-7-amide
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (7 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
7.3
-
pH 7.3, 37°C

References & Links

Links to other databases for Kallidin

ChEBI
PubChem
ChEBI
PubChem