Ligand view of benzyl isothiocyanate (5526 - MDKCFLQDBWCQCV-UHFFFAOYSA-N)

C₈H₇NS

benzyl isothiocyanate

MDKCFLQDBWCQCV-UHFFFAOYSA-N

MetaCyc

aromatic glucosinolate activation

5.3.99.2

benzyl isothiocyanate + glutathione = ?

649720

-

5.99.1.1

Benzyl isothiocyanate = ?

-

benzyl isothiocyanate + glutathione = ?

649720, 747503, 649654

-

5.99.1.1

2 entries

3.2.1.147

benzylglucosinolate + H2O = benzylisothiocyanate + D-glucose + ?

-

-

-

0.0033 mM, 50% inhibition after 30 min preincubation in assay with 5,5'-dithiobis(2-nitrobenzoic acid) as substrate

-

-

-

specific inhibition of MIF tautomerase activity is mediated by selective modification of the N-terminal proline

702357

-

5.3.3.12

specific inhibition of MIF tautomerase activity is mediated by selective modification of the N-terminal proline

702357

-

1.8.1.7

0.029

-

25°C, 30 min preincubation

685442

1.8.1.9

0.0033

-

25°C, 30 min preincubation in assay with 5,5'-dithiobis(2-nitrobenzoic acid) as substrate

685442

2.3.1.5

0.007

-

at pH 7.5 and 37°C

736924

5.3.2.1

0.0008

-

702357

5.3.3.12

0.0008

-

702357

3790

13997458

On enzymic and chemical reactions in crushed plants

1962

Virtanen A.I.

Arch. Biochem. Biophys.

Suppl 1

200-208

649654

-

Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class sigma glutathione S-transferase

1998

Thomson, A.M.; Meyer, D.J.; Hayes, J.D.

Biochem. J.

333

317-325

649720

11672424

Mammalian class Sigma glutathione S-transferases: catalytic properties and tissue-specific expression of human and rat GSH-dependent prostaglandin D2 synthases

2001

Jowsey, I.R.; Thomson, A.M.; Flanagan, J.U.; Murdock, P.R.; Moore, G.B.T.; Meyer, D.J.; Murphy, G.J.; Smith, S.A.; Hayes, J.D.

Biochem. J.

359

507-516

676480

16538523

Characterization of two Arabidopsis thaliana glutathione S-transferases

2006

Nutricati, E.; Miceli, A.; Blando, F.; De Bellis, L.

Plant Cell Rep.

25

997-1005

685442

17937621

Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents

2007

Hu, Y.; Urig, S.; Koncarevic, S.; Wu, X.; Fischer, M.; Rahlfs, S.; Mersch-Sundermann, V.; Becker, K.

Biol. Chem.

388

1069-1081

702357

19737008

A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor

2009

Ouertatani-Sakouhi, H.; El-Turk, F.; Fauvet, B.; Roger, T.; Le Roy, D.; Karpinar, D.P.; Leng, L.; Bucala, R.; Zweckstetter, M.; Calandra, T.; Lashuel, H.A.

Biochemistry

48

9858-9870

702461

20097269

Residue 234 is a master switch of the alternative-substrate activity profile of human and rodent theta class glutathione transferase T1-1

2010

Shokeer, A.; Mannervik, B.

Biochim. Biophys. Acta

1800

466-473

704872

19174456

Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily

2009

Dixon, D.P.; Hawkins, T.; Hussey, P.J.; Edwards, R.

J. Exp. Bot.

60

1207-1218

736924

26840026

Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine N-acetyltransferase-dependent acetylation and bioactivation of aromatic amine carcinogens

2016

Duval, R.; Xu, X.; Bui, L.C.; Mathieu, C.; Petit, E.; Cariou, K.; Dodd, R.H.; Dupret, J.M.; Rodrigues-Lima, F.

Oncotarget

7

8688-8699

737761

26026470

Substrate specificities of two tau class glutathione transferases inducible by 2,4,6-trinitrotoluene in poplar

2015

Musdal, Y.; Mannervik, B.

Biochim. Biophys. Acta

1850