Ligand 8-Azaxanthine

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Basic Ligand Information

Molecular Structure
Picture of 8-Azaxanthine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H3N5O2
8-Azaxanthine
KVGVQTOQSNJTJI-UHFFFAOYSA-N
Synonyms:
2,3-dihydrotriazolo[4,5-d]pyrimidine-5,7-dione, 5,7-dihydroxy-v-triazolo[4,5-d]pyrimidine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
8-azaxanthine + NAD+ + H2O = 8-aza-urate + NADH
show the reaction diagram
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5-phospho-alpha-D-ribose 1-diphosphate + 5,7-dihydroxy-v-triazolo[4,5-d]pyrimidine = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
8-azahypoxanthine + NAD+ + H2O = 8-azaxanthine + NADH
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (375 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
50% inhibition of ferricyanide reduction in xanthine oxidation assay at 5 mM
-

3D Structure of Enzyme-Ligand-Complex (PDB) (199 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.019
-
-

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.11
-
-

References & Links

Links to other databases for 8-Azaxanthine

ChEBI
PubChem
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PubChem