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Ligand (E)-pyridine-3-aldoxime

Basic Ligand Information

Molecular Structure

Related pathways

Show all BRENDA pathways known for (E)-pyridine-3-aldoxime

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

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Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

4.8.1.2

(E)-pyridine-3-aldoxime = ?

763288

-

4.8.1.2

(E)-pyridine-3-aldoxime = pyridine-3-nitrile + H2O

650189

-

4.8.1.2

2 entries

4.8.1.4

3-pyridine aldoxime = pyridine-3-carbonitrile + H2O

762990

-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

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Show Inhibitors (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

3.5.1.19

potent

246574

-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (1 result)

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Show Turnover Number (1 entry)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

4.8.1.4

0.873

-

at pH 6.0 and 35°C

762990

K_M Value (2 results)

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Show KM Value (2 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

4.8.1.2

20

-

pH 7, 30°C

650189

4.8.1.4

3.25

-

at pH 6.0 and 35°C

762990

References & Links

Literature References (6)

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Show Reference (6 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

246574

-

Inhibition of nicotinamide deaminase from Micrococcus lysodeikticus by analogues of nicotinamide

1974

Johnson, W.J.; Gadd, R.E.A.

Int. J. Biochem.

5

633-641

650189

14556637

A gene cluster responsible for alkylaldoxime metabolism coexisting with nitrile hydratase and amidase in Rhodococcus globerulus A-4

2003

Xie, S.X.; Kato, Y.; Komeda, H.; Yoshida, S.; Asano, Y.

Biochemistry

42

12056-12066

762990

34489036

Cyanide-free synthesis of aromatic nitriles from aldoximes Discovery and application of a novel heme-containing aldoxime dehydratase

2021

Chen, Z.; Mao, F.; Zheng, H.; Xiao, Q.; Ding, Z.; Wang, A.; Pei, X.

Enzyme Microb. Technol.

150

109883

762990

34489036

Cyanide-free synthesis of aromatic nitriles from aldoximes Discovery and application of a novel heme-containing aldoxime dehydratase

2021

Chen, Z.; Mao, F.; Zheng, H.; Xiao, Q.; Ding, Z.; Wang, A.; Pei, X.

Enzyme Microb. Technol.

150

109883

763288

16233624

Aldoxime dehydratase co-existing with nitrile hydratase and amidase in the iron-type nitrile hydratas(E)-producer Rhodococcus sp. N-771

2004

Kato, Y.; Yoshida, S.; Xie, S.X.; Asano, Y.

J. Biosci. Bioeng.

97

250-259

763288

16233624

Aldoxime dehydratase co-existing with nitrile hydratase and amidase in the iron-type nitrile hydratas(E)-producer Rhodococcus sp. N-771

2004

Kato, Y.; Yoshida, S.; Xie, S.X.; Asano, Y.

J. Biosci. Bioeng.

97

250-259

762990

2 entries

763288

2 entries

Links to other databases for (E)-pyridine-3-aldoxime

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Show Links (1 entry)