Ligand HIV1 Nef protein N-terminal peptide
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
HIV1 Nef protein N-terminal peptide
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
myristoyl-CoA + HIV1 Nef protein N-terminal peptide = N-myristoyl-HIV1 Nef protein N-terminal peptide + CoA
-
Inhibitor in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Nef peptide acts as a competitive inhibitor for the myristoylation of Gag; Nef peptide acts as a competitive inhibitor for the myristoylation of Gag
-
Enzyme Kinetic Parameters
kcat Value (Turnover Number) (2 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.032
-
pH 7.4, 37°C, isozyme NMT2
0.052
-
pH 7.4, 37°C, isozyme NMT1
KM Value (2 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.0015
-
pH 7.4, 37°C, isozyme NMT2
0.011
-
pH 7.4, 37°C, isozyme NMT1
References & Links
Literature References (1)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
N-Myristoyltransferase isozymes exhibit differential specificity for human immunodeficiency virus type 1 Gag and Nef
2008
Seaton, K.; Smith, C.
J. Gen. Virol.
89
288-296
Links to other databases for HIV1 Nef protein N-terminal peptide