Ligand D-arabinose 5-phosphate

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Basic Ligand Information

Molecular Structure
Picture of D-arabinose 5-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H11O8P
D-arabinose 5-phosphate
PPQRONHOSHZGFQ-WDCZJNDASA-N
Synonyms:
5-phospho-D-arabinose, arabinose-5-phosphate, arabinose 5-phosphate, D(-)arabinose 5-phosphate, D-arabinose-5-phosphate
Pathway Source
Pathways


Show all pahtways known for Show all BRENDA pathways known for D-arabinose 5-phosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-Arabinose 5-phosphate = D-Ribulose 5-phosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + D-arabinose = ADP + D-arabinose 5-phosphate
show the reaction diagram
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D-ribulose 5-phosphate = D-arabinose 5-phosphate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-arabinose 5-phosphate + NADPH + H+ = ? + NADP+
show the reaction diagram
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D-arabinose 5-phosphate + ? = ?
show the reaction diagram
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phosphoenolpyruvate + D-arabinose 5-phosphate = 3-deoxy-D-manno-octulosonate 8-phosphate + phosphate
show the reaction diagram
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D-arabinose 5-phosphate + H2O = D-arabinose + phosphate
show the reaction diagram
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Arabinose 5-phosphate + H2O = Arabinose + phosphate
show the reaction diagram
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D-Arabinose 5-phosphate = D-Ribulose 5-phosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + D-arabinose = ADP + D-arabinose 5-phosphate
show the reaction diagram
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ATP + D(-)-arabinose = ADP + D(-)arabinose 5-phosphate
show the reaction diagram
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D-ribulose 5-phosphate = D-arabinose 5-phosphate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
at higher concentrations
-
mutant enzyme R106G is less severely inhibited than wild-type enzyme
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weak
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3D Structure of Enzyme-Ligand-Complex (PDB) (27 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (56 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
2.3
-
wild-type, pH 7.2, 25C
2.92
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pH 7.0, 37C

KM Value (92 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
3
-
wild-type, pH 7.2, 25C
27.36
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pH 7.0, 37C

Ki Value (6 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0049
-
isoform ToTal1, 25C, pH 8.5
3.62
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forward reaction, pH 8.0, 25C

References & Links

Links to other databases for D-arabinose 5-phosphate

ChEBI
PubChem
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PubChem