Ligand L-sorbitol

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of L-sorbitol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H14O6
L-sorbitol
FBPFZTCFMRRESA-FSIIMWSLSA-N
Synonyms:
D-Gulitol, L-glucitol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-glucitol + NAD+ = ? + NADH
show the reaction diagram
-
L-glucitol + NAD+ = D-sorbose + NADH + H+
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-sorbitol + NAD+ = ? + NADH
show the reaction diagram
-
L-glucitol + NAD+ = D-sorbose + NADH + H+
show the reaction diagram
-
L-glucitol + NAD+ = ? + NADH
show the reaction diagram
-
L-sorbitol + NAD+ = ?
show the reaction diagram
-
L-sorbitol + NAD+ = L-sorbose + NADH + H+
show the reaction diagram
-
L-glucitol + NAD+ = D-sorbose + NADH + H+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-sorbose + NADPH + H+ = L-sorbitol + NADP+
show the reaction diagram
-
-
D-sorbose + NADH = D-gulitol + NAD+
show the reaction diagram
-
-
L-sorbose + NADPH = L-sorbitol + NADP+
show the reaction diagram
-
-
L-sorbose + NADH + H+ = L-sorbitol + NAD+
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
Ki: 24.6 mM
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
60
-
pH 10.0, 25°C

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
19
-
pH 8.6, 25°C
178
-
pH 9, 30°C
680
-
pH 10.0, 25°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
24.6
-
-

References & Links

Links to other databases for L-sorbitol

ChEBI
PubChem
-
PubChem