Ligand benzylamine

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Basic Ligand Information

Molecular Structure
Picture of benzylamine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H9N
benzylamine
OFEZSBMBBKLLBJ-BAJZRUMYSA-N
Synonyms:
1-phenylmethanamine, 1-phenylmethaneamine, Substituted benzylamines

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzylamine + [reduced NADPH-hemoprotein reductase] + O2 = benzylamine N-oxide + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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benzylamine + H2O + O2 = benzaldehyde + NH3 + H2O2
show the reaction diagram

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-benzylformamide + H2O = formate + benzylamine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (22 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzylamine + [reduced NADPH-hemoprotein reductase] + O2 = benzylamine N-oxide + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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benzylamine + FADH2 + O2 = N-(benzyl)hydroxylamine + FAD + H2O
show the reaction diagram
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benzylamine + O2 + H2O = benzaldehyde + NH3 + H2O2
show the reaction diagram
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benzylamine + O2 + H2O = benzaldehyde + NH3 + H2O2
show the reaction diagram
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benzylamine + O2 + H2O = benzaldehyde + NH3 + H2O2
show the reaction diagram
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benzylamine + H2O + O2 = benzaldehyde + NH3 + H2O2
show the reaction diagram
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Z-Gln-Gly + benzylamine = ?
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benzylamine + pyruvate = benzaldehyde + L-alanine
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2-oxobutyrate + benzylamine = L-homoalanine + benzaldehyde
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pyruvate + benzylamine = L-alanine + benzaldehyde
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2 rac-N-tert-butoxycarbonylphenylalanine ethyl thioester + 1-phenylmethanamine + tert-butanol = N-benzyl-Nalpha-(tert-butoxycarbonyl)-L-phenylalaninamide + (R)-N-tert-butoxycarbonylphenylalanine ethyl thioester + ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5'-phospho-pyridoxyl-benzylamine + H2O + O2 = pyridoxal 5'-phosphate + benzylamine + H2O2
show the reaction diagram
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benzaldehyde + ortho-xylylenediamine = benzylamine + ?
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D-alanine benzylamide + H2O = D-Ala + benzylamine
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Pro-Phe-Arg benzylamide + H2O = Pro-Phe-Arg + benzylamine
show the reaction diagram
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benzyladenine + H2O = hypoxanthine + 1-phenylmethaneamine
show the reaction diagram
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L-gamma-glutamylbenzylamine = benzylamine + 5-oxo-L-proline
show the reaction diagram
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5-L-glutamyl-benzylamine = 5-oxoproline + benzylamine
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates sQH-AmDH
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Inhibitor in Enzyme-catalyzed Reactions (20 results)

3D Structure of Enzyme-Ligand-Complex (PDB) (69 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (44 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (86 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
53.6
-
pH 7.0, 25°C

Ki Value (5 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.047
-
-
0.17
-
pH 8.0, 37°C
0.01281
-
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IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0647
-
LOXL2 protein, at pH 8.0 and 37°C

References & Links

Links to other databases for benzylamine

ChEBI
PubChem
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PubChem