Ligand 13-cis-retinol

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Basic Ligand Information

Molecular Structure
Picture of 13-cis-retinol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H30O
13-cis-retinol
FPIPGXGPPPQFEQ-HWCYFHEPSA-N
Synonyms:
13-cis-retinol1, 13-cis retinol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
13-cis-retinol + NAD+ = 13-cis-retinal + NADH + H+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
an all-trans-retinyl ester + H2O = 13-cis-retinol + a fatty acid
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
13-cis-retinol + NAD+ = 13-cis-retinal + NADH
show the reaction diagram
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13-cis-retinol + NAD+ = 13-cis-retinal + NADH + H+
show the reaction diagram
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13-cis-retinol + NADP+ = 13-cis-retinal + NADPH + H+
show the reaction diagram
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palmitoyl-CoA + 13-cis-retinol = ?
show the reaction diagram
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myristoyl-CoA + 13-cis-retinol = 13-cis-retinyl myristate + CoA
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
13-cis-retinal + NADH + H+ = 13-cis-retinol + NAD+
show the reaction diagram
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13-cis-retinal + NADPH = 13-cis-retinol + NADP+
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.018
-
oxidation with NAD+

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.257
-
oxidation with NAD+
0.0188
-
at pH 8.0 and 37°C
0.03518
-
at pH 7.0 and 37°C

References & Links

Links to other databases for 13-cis-retinol

ChEBI
PubChem
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PubChem