Ligand dTTP

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Basic Ligand Information

Molecular Structure

C₁₀H₁₇N₂O₁₄P₃

dTTP

NHVNXKFIZYSCEB-XLPZGREQSA-N

Synonyms:

2'-deoxy-beta-L-thymidine-5'-triphosphate, 2'-deoxythymidine 5'-triphosphate, 2'-dTTP, 5'-dTTP, D-beta-deoxythymidine-triphosphate, deoxythymidine 5'-triphosphate, thymidine 5'-triphosphate, thymidine triphosphate, TTP

BRENDA

dTDPLrhamnose biosynthesis, macrolide antibiotic biosynthesis, pyrimidine metabolism

KEGG

Nucleotide metabolism, Pyrimidine metabolism

MetaCyc

dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis, dTDP-3-acetamido-alpha-D-fucose biosynthesis, dTDP-4-O-demethyl-beta-L-noviose biosynthesis, dTDP-6-deoxy-alpha-D-allose biosynthesis, dTDP-alpha-D-forosamine biosynthesis

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Show all BRENDA pathways known for dTTP

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (20 results)

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2.7.7.24

14 entries

2.7.7.64

TTP + alpha-D-glucose 1-phosphate = diphosphate + TDP-D-glucose

721524

2.7.7.9

dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-alpha-D-glucose

dTTP + H2O = dTDP + phosphate

210043, 210047, 210048, 210049, 210044, 210045, 210046, 210050, 210051, 688933, 697608

3.6.1.5

TTP + 2 H2O = TMP + 2 phosphate

700083

In Vivo Product in Enzyme-catalyzed Reactions (12 results)

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2.7.1.40

TDP + phosphoenolpyruvate = TTP + pyruvate

2.7.4.1

TDP + (phosphate)n+1 = TTP + (phosphate)n

645125

2.7.4.3

ADP + TDP = AMP + TTP

Substrate in Enzyme-catalyzed Reactions (805 results)

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1.1.98.6

TTP + formate = dTTP + CO2 + H2O

740665

2.6.99.1

dTTP + depurinated DNA = deoxyribose triphosphate + purinated DNA

640205

2.7.1.1

TTP + D-glucose = TDP + D-glucose 6-phosphate

676958, 739403

2.7.1.11

TTP + D-fructose 6-phosphate = TDP + D-fructose 1,6-bisphosphate

TTP + D-tagatose 6-phosphate = TDP + D-tagatose 1,6-bisphosphate

640993

2.7.1.165

TTP + (R)-glycerate = TDP + 2-phospho-(R)-glycerate

685823

2.7.1.20

TTP + adenosine = TDP + AMP

TTP + 3'-dephospho-CoA = TDP + CoA

759246

2.7.1.30

TTP + glycerol = TDP + glycerol 3-phosphate

641289

2.7.1.33

pantothenate + dTTP = 4'-phosphopantothenate + dTDP

TTP + D-fructose = TDP + D-fructose 6-phosphate

641501, 662020

2.7.1.45

TTP + 2-dehydro-3-deoxy-D-gluconate = TDP + 6-phospho-2-dehydro-3-deoxy-D-gluconate

676988

2.7.1.48

dTTP + uridine = dTDP + UMP

641643

2.7.1.50

TTP + 4-methyl-5-(2-hydroxyethyl)thiazole = TDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

737878

2.7.1.56

TTP + D-fructose 1-phosphate = TDP + D-fructose 1,6-bisphosphate

640483, 727057

2.7.1.6

dTTP + D-galactose = ?

721979

2.7.1.63

TTP + glucose = TDP + D-glucose 6-phosphate

641755

2.7.1.67

TTP + 1-phosphatidyl-1D-myo-inositol = TDP + 1-phosphatidyl-1D-myo-inositol 4-phosphate

641787

2.7.1.7

TTP + D-mannose = TDP + D-mannose 6-phosphate

TTP + 5'-dephospho-DNA = TDP + 5'-phospho-DNA

642004

2.7.1.B20

TTP + inosine = TDP + inosine 5'-phosphate

697882

2.7.2.1

TTP + acetate = TDP + acetyl phosphate

642178, 642184, 727804, 730304

2.7.2.3

2'-dTTP + 3-phospho-D-glycerate = 2'-dTDP + 3-phospho-D-glyceroyl phosphate

TTP + (R,S)-5-phosphomevalonate = TDP + (R,S)-5-diphosphomevalonate

dTTP + dTMP = dTDP

dTTP + UMP = dTDP + UDP

663751

2.7.4.B7

dTTP + (phosphate)n = dTDP + (phosphate)n+1

762661

2.7.7.13

dTTP + alpha-D-mannose 1-phosphate = alpha-dTDP-mannose + diphosphate

dTTP + alpha-D-galactose 1-phosphate = dTDPgalactose + ?

dTTP + tobramycin = diphosphate + 2''-deoxythymidylyltobramycin

dTTP + RNAn = ?

dTTP + valienol 1-phosphate = diphosphate + dTDP-valienol

dTTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + dTDP-N-acetyl-alpha-D-glucosamine

dTTP + H2O = ?

TTP + H2O = ?

thymidine 5'-triphosphate + H2O = ?

208385

3.1.5.B1

dTTP + H2O = deoxythymidine + triphosphate

749906, 730044

3.6.1.1

TTP + H2O = ? + phosphate

677801

3.6.1.12

dTTP + H2O = dTMP + diphosphate

722230, 733297, 734816

3.6.1.15

3 entries

3.6.1.23

dTTP + H2O = dTMP + diphosphate

656212, 711327, 209996, 209998, 209990, 648212, 756316, 209997, 657286

dTTP + H2O = ?

dTTP + H2O = dTMP + diphosphate

dTTP + H2O = dTDP + phosphate

695264

4.1.1.49

TTP + oxaloacetate = TDP + phosphoenolpyruvate + CO2

4636

5.6.1.2

TTP + H2O + a dynein associated with a microtubule at position n = TDP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)

247009, 247007

5.6.1.5

TTP + H2O + polypeptide = TDP + phosphate + unfolded polypeptide

210605