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The role of Saccharomyces cerevisiae MET1p and MET8p in sirohaem and cobalamin biosynthesis
1999
Raux, E.; McVeigh, T.; Peters, S.E.; Leustek, T.; Warren, M.J.
Biochem. J.
338
701-708
The structure of Saccharomyces cerevisiae Met8p, a bifunctional dehydrogenase and ferrochelatase
2002
Schubert, H.L.; Raux, E.; Brindley, A.A.; Leech, H.K.; Wilson, K.S.; Hill, C.P.; Warren, M.J.
EMBO J.
21
2068-2075
Common chelatase design in the branched tetrapyrrole pathways of heme and anaerobic cobalamin synthesis
1999
Schubert, H.L.; Raux, E.; Wilson, K.S.; Warren, M.J.
Biochemistry
38
10660-10669
A story of chelatase evolution: Identification and characterisation of a small 13-15 kDa 'ancestral' cobaltochelatase (CbiXS) in the Archaea
2003
Brindley, A.A.; Raux E.; Leech, H.K.; Schubert, H.L.; Warren, M.J.
J. Biol. Chem.
278
22388-22395
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Gene dissection demonstrates that the Escherichia coli cysG gene encodes a multifunctional protein
1994
Warren, M.J.; Bolt, E.L.; Roessner, C.A.; Scott, A.I.; Spencer, J.B.; Woodcock, S.C.
Biochem. J.
302
837-844
Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium
2003
Raux, E.; Leech, H.K.; Beck, R.; Schubert, H.L.; Santander, P.J.; Roessner, C.A.; Scott, A.I.; Martens, J.H.; Jahn, D.; Thermes, C.; Rambach, A.; Warren, M.J.
Biochem. J.
370
505-516
Structural diversity in metal ion chelation and the structure of uroporphyrinogen III synthase
2002
Schubert, H.L.; Raux, E.; Matthews, M.A.; Phillips, J.D.; Wilson, K.S.; Hill, C.P.; Warren, M.J.
Biochem. Soc. Trans.
30
595-600
Production of cobalamin and sirohaem in Bacillus megaterium: an investigation into the role of the branchpoint chelatases sirohydrochlorin ferrochelatase (SirB) and sirohydrochlorin cobalt chelatase (CbiX)
2002
Leech, H.K.; Raux-Deery, E.; Heathcote, P.; Warren, M.J.
Biochem. Soc. Trans.
30
610-613
Biosynthesis of cobalamin (vitamin B12): a bacterial conundrum
2000
Raux, E.; Schubert, H.L.; Warren, M.J.
Cell. Mol. Life Sci.
57
1880-1893
Evidence that the CysG protein catalyzes the first reaction specific to B12 synthesis in Salmonella typhimurium, insertion of cobalt
1996
Fazzio, T.G.; Roth, J.R.
J. Bacteriol.
178
6952-6959
A role for Salmonella typhimurium cbiK in cobalamin (vitamin B12) and siroheme biosynthesis
1997
Raux, E.; Thermes, C.; Heathcote, P.; Rambach, A.; Warren, M.J.
J. Bacteriol.
179
3202-3212
A cysG mutant strain of Rhizobium etli pleiotropically defective in sulfate and nitrate assimilation
1997
Tate, R.; Riccio, A.; Iaccarino, M.; Patriarca, E.J.
J. Bacteriol.
179
7343-7350
Characterization of the cobaltochelatase CbiXL: evidence for a 4Fe-4S center housed within an MXCXXC motif
2003
Leech, H.K.; Raux, E.; McLean, K.J.; Munro, A.W.; Robinson, N.J.; Borrelly, G.P.; Malten, M.; Jahn, D.; Rigby, S.E.; Heathcote, P.; Warren, M.J.
J. Biol. Chem.
278
41900-41907
CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis
2003
Stroupe, M.E.; Leech, H.K.; Daniels, D.S.; Warren, M.J.; Getzoff, E.D.
Nat. Struct. Biol.
10
1064-1073
Identification and characterization of the terminal enzyme of siroheme biosynthesis from Arabidopsis thaliana: a plastid-located sirohydrochlorin ferrochelatase containing a 2FE-2S center
2005
Raux-Deery, E.; Leech, H.K.; Nakrieko, K.A.; McLean, K.J.; Munro, A.W.; Heathcote, P.; Rigby, S.E.; Smith, A.G.; Warren, M.J.
J. Biol. Chem.
280
4713-4721
Crystal structure of the vitamin B12 biosynthetic cobaltochelatase, CbiXS, from Archaeoglobus fulgidus
2006
Yin, J.; Xu, L.X.; Cherney, M.M.; Raux-Deery, E.; Bindley, A.A.; Savchenko, A.; Walker, J.R.; Cuff, M.E.; Warren, M.J.; James, M.N.
J. Struct. Funct. Genomics
7
37-50
Probing the structural plasticity of an archaeal primordial cobaltochelatase CbiXS
2007
Pisarchik, A.; Petri, R.; Schmidt-Dannert, C.
Protein Eng. Des. Sel.
20
257-265
Two distinct roles for two functional cobaltochelatases (CbiK) in Desulfovibrio vulgaris Hildenborough
2008
Lobo, S.A.; Brindley, A.A.; Romao, C.V.; Leech, H.K.; Warren, M.J.; Saraiva, L.M.
Biochemistry
47
5851-5857
The AAA(+) motor complex of subunits CobS and CobT of cobaltochelatase visualized by single particle electron microscopy
2009
Lundqvist, J.; Elmlund, D.; Heldt, D.; Deery, E.; Soederberg, C.A.; Hansson, M.; Warren, M.; Al-Karadaghi, S.
J. Struct. Biol.
167
227-234
Evolution in a family of chelatases facilitated by the introduction of active site asymmetry and protein oligomerization
2011
Romao, C.V.; Ladakis, D.; Lobo, S.A.; Carrondo, M.A.; Brindley, A.A.; Deery, E.; Matias, P.M.; Pickersgill, R.W.; Saraiva, L.M.; Warren, M.J.
Proc. Natl. Acad. Sci. USA
108
97-102
Characterization of the evolutionarily conserved iron-sulfur cluster of sirohydrochlorin ferrochelatase from Arabidopsis thaliana
2012
Saha, K.; Webb, M.E.; Rigby, S.E.; Leech, H.K.; Warren, M.J.; Smith, A.G.
Biochem. J.
444
227-237
Identification and characterization of the missing terminal enzyme for siroheme biosynthesis in alpha-proteobacteria
2014
Bali, S.; Rollauer, S.; Roversi, P.; Raux-Deery, E.; Lea, S.M.; Warren, M.J.; Ferguson, S.J.
Mol. Microbiol.
92
153-163
Towards a cell factory for vitamin B12 production in Bacillus megaterium: bypassing of the cobalamin riboswitch control elements
2014
Moore, S.J.; Mayer, M.J.; Biedendieck, R.; Deery, E.; Warren, M.J.
New Biotechnol.
31
553-561
Elucidation of the biosynthesis of the methane catalyst coenzyme F430
2017
Moore, S.J.; Sowa, S.T.; Schuchardt, C.; Deery, E.; Lawrence, A.D.; Ramos, J.V.; Billig, S.; Birkemeyer, C.; Chivers, P.T.; Howard, M.J.; Rigby, S.E.; Layer, G.; Warren, M.J.
Nature
543
78-82
The biosynthetic pathway of coenzyme F430 in methanogenic and methanotrophic archaea
2016
Zheng, K.; Ngo, P.; Owens, V.; Yang, X.; Mansoorabadi, S.
Science
354
339-342
Siroheme synthase orients substrates for dehydrogenase and chelatase activities in a common active site
2020
Pennington, J.; Kemp, M.; McGarry, L.; Chen, Y.; Stroupe, M.
Nat. Commun.
11
864
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