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2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine, N-(2,4-diamino-6-hydroxypyrimidin-5-yl)-N-methylformamide, N-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-N-methylformamide
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Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and overproduction of the protein
1987
Boiteux, S.; O'Connor, T.R.; Laval, J.
EMBO J.
6
3177-3183
The catalytic mechanism of Fpg protein. Evidence for a Schiff base intermediate and amino terminus localization of the catalytic site
1995
Tchou, J.; Grollman, A.P.
J. Biol. Chem.
270
11671-11677
Substrate specificity of Fpg protein. Recognition and cleavage of oxidatively damaged DNA
1994
Tchou, J.; Bodepudi, V.; Shibutani, S.; Antoshechkin, I.; Miller, J.; Grollman, A.P.; Johnson, F.
J. Biol. Chem.
269
15318-15324
8-Oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity
1991
Tchou, J.; Kasai, H.; Chung, M.H.; Laval, J.; Grollman, A.P.; Nishimura, S.
Proc. Natl. Acad. Sci. USA
88
4690-4694
Physical association of the 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase of Escherichia coli and an activity nicking DNA at apurinic/apyrimidinic sites
1989
O'Connor, T.R.; Laval, J.
Proc. Natl. Acad. Sci. USA
86
5222-5226
Mechanism of DNA strand nicking at apurinic/apyrimidinic sites by Escherichia coli [formamidopyrimidine]DNA glycosylase
1989
Bailly, V.; Verly, W.G.; O'Connor, T.; Laval, J.
Biochem. J.
262
581-589
Purification and characterization of Escherichia coli formamidopyrimidine-DNA glycosylase that excises damaged 7-methylguanine from deoxyribonucleic acid
1981
Chetsanga, C.J.; Lozon, M.; Makaroff, C.; Savage, L.
Biochemistry
20
5201-5207
New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase
1994
Hatahet, Z.; Kow, Y.W.; Purmal, A.A.; Cunningham, R.P.; Wallace, S.S.
J. Biol. Chem.
269
18814-18820
Repair of oxidative DNA damage in gram-positive bacteria: the Lactococcus lactis Fpg protein
1995
Duwat, P.; de Oliveira, R.; Ehrlich, S.D.; Boiteux, S.
Microbiology
141
411-417
Effect of single mutations on the specificity of Escherichia coli FPG protein for excision of purine lesions from DNA damaged by free radicals
2001
Sidorkina, O.; Dizdaroglu, M.; Laval, J.
Free Radic. Biol. Med.
31
816-823
Mechanism of action of base release by Escherichia coli Fpg protein: Role of lysine 155 in catalysis
1997
Rabow, L.E.; Kow, Y.W.
Biochemistry
36
5084-5096
Distinct repair activities of human 7,8-dihydro-8-oxoguanine DNA glycosylase and formamidopyrimidine DNA glycosylase for formamidopyrimidine and 7,8-dihydro-8-oxoguanine
2000
Asagoshi, K.; Yamada, T.; Terato, H.; Ohyama, Y.; Monden, Y.; Arai, T.; Nishimura, S.; Aburatani, H.; Lindahl, T.; Ide, H.
J. Biol. Chem.
275
4956-4964
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