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Ligand isofucosterol Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C2 9 H4 8 O
isofucosterol
OSELKOCHBMDKEJ-WGMIZEQOSA-N
24-ethylidenecholesterol, stigmasta-5,24(28)-dien-3beta-ol
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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isofucosterol + NADPH = sitosterol + NADP+
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Substrate in Enzyme-catalyzed Reactions (4 results)
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isofucosterol + NADPH = sitosterol + NADP+
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isofucosterol + NADPH + H+ = sitosterol + NADP+
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UDP-glucose + isofucosterol = UDP + isofucosterol 3-beta-glucoside
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stigmasta-5,24(28)-dien-3beta-ol + UDP-glucose = ?
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Product in Enzyme-catalyzed Reactions (1 result)
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24-methylenecholesterol + S-adenosyl-L-methionine = 24-ethylidenecholesterol + S-adenosyl-L-homocysteine
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Enzyme Kinetic Parameters
References & Links Literature References (5)
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A sterol methyltransferase from bean rust uredospores Uromyces phaseoli
1976
Lin, H.K.; Knoche, H.W.
Phytochemistry
15
683-687
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Phospholipid-dependence of plant UDP-glucose-sterol-beta-D-glucosyltransferase. II. Acetone-mediated delipidation and kinetic studies
1984
Ullmann, P.; Rimmele, D.; Benveniste, P.; Bouvier-Nave, P.
Plant Sci. Lett.
36
29-36
Sterols regulate development and gene expression in Arabidopsis
2003
He, J.X.; Fujioka, S.; Li, T.C.; Kang, S.G.; Seto, H.; Takatsuto, S.; Yoshida, S.; Jang, J.C.
Plant Physiol.
131
1258-1269
Metabolism of conjugated sterols in eggplant. Part 1. UDP-glucose:sterol glucosyltransferase
2008
Potocka, A.; Zimowski, J.
Acta Biochim. Pol.
55
127-134
Plant sterol metabolism. DELTA7-Sterol-C5-desaturase (STE1/DWARF7), DELTA5,7-sterol-DELTA7-reductase (DWARF5) and DELTA24-sterol-DELTA24-reductase (DIMINUTO/DWARF1) show multiple subcellular localizations in Arabidopsis thaliana (Heynh) L
2013
Silvestro, D.; Andersen, T.G.; Schaller, H.; Jensen, P.E.
PLoS ONE
8
e56429
Links to other databases for isofucosterol