Ligand Hypotaurine

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Basic Ligand Information

Molecular Structure
Picture of Hypotaurine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C2H7NO2S
Hypotaurine
IGCZFSMEIXUSJY-FKUSVXTQSA-N
Synonyms:
2-Aminoethane sulfinate, 2-aminoethanesulfinic acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
hypotaurine + H2O + NAD+ = taurine + NADH
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
hypotaurine + H2O + phenazine methosulfate = ? + NH3 + reduced phenazine methosulfate
show the reaction diagram
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Hypotaurine + pyruvate + NADH = N2-(1-Carboxyethyl)aminoethanesulfinic acid + NAD+ + H2O
show the reaction diagram
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hypotaurine + H2O + NAD+ = taurine + NADH
show the reaction diagram
-
acetyl-CoA + 2-aminoethanesulfinic acid = CoA + ?
show the reaction diagram
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hypotaurine + 2-oxoglutarate = L-glutamate + 2-oxoethanesulfinic acid
show the reaction diagram
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hypotaurine + 2-oxoglutarate = 2-oxoethanesulfinic acid + L-glutamate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
hypotaurine + pyruvate = 2-aminoethanesulfinic acid + L-alanine
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
20
-
pH 7.5, 25C

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
16.4
-
pH 7.5, 25C
8.1
-
pH 9.0, 35C

References & Links

Links to other databases for Hypotaurine

ChEBI
PubChem
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PubChem