Ligand D-mannosamine

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Basic Ligand Information

Molecular Structure
Picture of D-mannosamine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H13NO5
D-mannosamine
MSWZFWKMSRAUBD-CBPJZXOFSA-N
Synonyms:
2-amino-2-deoxy-D-mannose, mannopyranosylamine, mannosamine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-amino-2-deoxy-D-mannose + NADP+ = 2-amino-2-deoxy-D-mannono-1,5-lactone + NADPH
show the reaction diagram
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D-mannosamine + O2 = ?
show the reaction diagram
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ATP + D-mannosamine = ADP + D-mannosamine 6-phosphate
show the reaction diagram
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ATP + D-mannosamine = ADP + alpha-D-mannosamine 1-phosphate
show the reaction diagram
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mannopyranosylamine + H2O = ?
show the reaction diagram
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D-mannosamine + pyruvate = ?
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
does not bind directly or efficiently to the active site of the enzyme, but interferes indirectly with the enzyme’s access to GDP-Man
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complete inhibition at 1% versus 1% sucrose
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1.5 mM
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Enzyme Kinetic Parameters

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
5
-
at 37°C, pH 7.4
20
-
pH 7.5, 25°C

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for D-mannosamine

ChEBI
PubChem
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PubChem