Ligand alpha-lactose

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Basic Ligand Information

Molecular Structure
Picture of alpha-lactose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H22O11
alpha-lactose
GUBGYTABKSRVRQ-XLOQQCSPSA-N
Synonyms:
4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose, alpha-D-lactose, beta-D-Gal-(1->4)-alpha-D-Glc

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + lactose/out = ADP + phosphate + lactose/in
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + lactose/out = ADP + phosphate + lactose/in
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alpha-D-lactose + phenazine methosulfate = alpha-D-lactono-1,5-lactone + reduced phenazine methosulfate
show the reaction diagram
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cytidine 5'-monophosphate 3-(axial)-fluoro-N-acetylneuraminic acid + alpha-lactose = ?
show the reaction diagram
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CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->4)-alpha-D-Glc = CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-alpha-D-Glc
show the reaction diagram
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alpha-lactose + H2O = D-galactose + D-glucose
show the reaction diagram
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alpha-lactose = beta-lactose
show the reaction diagram
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ATP + H2O + lactose/out = ADP + phosphate + lactose/in
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
beta-Lactose = alpha-Lactose
show the reaction diagram
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ATP + H2O + lactose/out = ADP + phosphate + lactose/in
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (26 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (7 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for alpha-lactose

ChEBI
PubChem
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PubChem