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Purification and properties of malate dehydrogenase from Pseudomonas testosteroni
1975
You, K.S.; Kaplan, N.O.
J. Bacteriol.
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Identification of an archaeal 2-hydroxy acid dehydrogenase catalyzing reactions involved in coenzyme biosynthesis in methanoarchaea
2000
Graupner, M.; Xu, H.; White, R.H.
J. Bacteriol.
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Purification and characterization of a-hydroxyglutarate dehydrogenase from Alcaligenes sp.
1985
Suzuki, T.; Uozomi, T.; Beppu, T.
Agric. Biol. Chem.
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L-2-Hydroxyglutarate dehydrogenase: identification of a novel enzyme activity in rat and human liver. Implications for L-2-hydroxyglutaric acidemia
1993
Jansen, G.A.; Wanders, R.J.A.
Biochim. Biophys. Acta
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Glutamate synthase (NADH) from lupin nodules. Specificity of the 2-oxoglutarate site
1981
Boland, M.J.; Court, C.B.
Biochim. Biophys. Acta
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Glutaconate CoA-transferase from Acidaminococcus fermentans
1981
Buckel, W.; Dorn, U.; Semmler, R.
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Rearrangement of L-2-hydroxyglutarate to L-threo-3-methylmalate catalyzed by adenosylcobalamin-dependent glutamate mutase
2000
Roymoulik, I.; Moon, N.; Dunham, W.R.; Ballou, D.P.; Marsh, E.N.
Biochemistry
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Identification of a dehydrogenase acting on D-2-hydroxyglutarate
2004
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Biochem. J.
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A gene encoding a putative FAD-dependent L-2-hydroxyglutarate dehydrogenase is mutated in L-2-hydroxyglutaric aciduria
2004
Rzem, R.; Veiga-da-Cunha, M.; Noel, G.; Goffette, S.; Nassogne, M.C.; Tabarki, B.; Scholler, C.; Marquardt, T.; Vikkula, M.; Van Schaftingen, E.
Proc. Natl. Acad. Sci. USA
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The gene mutated in L-2-hydroxyglutaric aciduria encodes L-2-hydroxyglutarate dehydrogenase
2006
Rzem, R.; Van Schaftingen, E.; Veiga-da-Cunha, M.
Biochimie
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Toward an improved understanding of the glutamate mutase system
2007
Sandala, G.M.; Smith, D.M.; Marsh, E.N.; Radom, L.
J. Am. Chem. Soc.
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Identification of Escherichia coli YgaF as an L-2-hydroxyglutarate oxidase
2008
Kalliri, E.; Mulrooney, S.B.; Hausinger, R.P.
J. Bacteriol.
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Development and implementation of a novel assay for L-2-hydroxyglutarate dehydrogenase (L-2-HGDH) in cell lysates: L-2-HGDH deficiency in 15 patients with L-2-hydroxyglutaric aciduria
2009
Kranendijk, M.; Salomons, G.S.; Gibson, K.M.; Aktuglu-Zeybek, C.; Bekri, S.; Christensen, E.; Clarke, J.; Hahn, A.; Korman, S.H.; Mejaski-Bosnjak, V.; Superti-Furga, A.; Vianey-Saban, C.; van der Knaap, M.S.; Jakobs, C.; Struys, E.A.
J. Inherit. Metab. Dis.
32
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An overview of L-2-hydroxyglutarate dehydrogenase gene (L2HGDH) variants: a genotype-phenotype study
2010
Steenweg, M.E.; Jakobs, C.; Errami, A.; van Dooren, S.J.; Adeva Bartolome, M.T.; Aerssens, P.; Augoustides-Savvapoulou, P.; Baric, I.; Baumann, M.; Bonafe, L.; Chabrol, B.; Clarke, J.T.; Clayton, P.; Coker, M.; Cooper, S.; Falik-Zaccai, T.; Gorman, M.; Hahn, A.; Hasanoglu, A.; King, M.D.; de Klerk, H.
Hum. Mutat.
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High-temperature sorbose fermentation with thermotolerant Gluconobacter frateurii CHM43 and its mutant strain adapted to higher temperature
2012
Hattori, H.; Yakushi, T.; Matsutani, M.; Moonmangmee, D.; Toyama, H.; Adachi, O.; Matsushita, K.
Appl. Microbiol. Biotechnol.
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Disruption of the membrane-bound alcohol dehydrogenase-encoding gene improved glycerol use and dihydroxyacetone productivity in Gluconobacter oxydans
2010
Habe, H.; Fukuoka, T.; Morita, T.; Kitamoto, D.; Yakushi, T.; Matsushita, K.; Sakaki, K.
Biosci. Biotechnol. Biochem.
74
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Multiple turnovers of the nicotino-enzyme PdxB require alpha-keto acids as cosubstrates
2010
Rudolph, J.; Kim, J.; Copley, S.D.
Biochemistry
49
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Plants possess a cyclic mitochondrial metabolic pathway similar to the mammalian metabolic repair mechanism involving malate dehydrogenase and l-2-hydroxyglutarate dehydrogenase
2015
Huedig, M.; Maier, A.; Scherrers, I.; Seidel, L.; Jansen, E.E.; Mettler-Altmann, T.; Engqvist, M.K.; Maurino, V.G.
Plant Cell Physiol.
56
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A scalable lysyl hydroxylase 2 expression system and luciferase-based enzymatic activity assay
2017
Guo, H.F.; Cho, E.J.; Devkota, A.K.; Chen, Y.; Russell, W.; Phillips, G.N.; Yamauchi, M.; Dalby, K.N.; Kurie, J.M.
Arch. Biochem. Biophys.
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L-2-hydroxyglutarate dehydrogenase identification of a novel enzyme activity in rat and human liver. Implications for L-2-hydroxyglutaric acidemia
1993
Jansen, G.A.; Wanders, R.J.
Biochim. Biophys. Acta
1225
53-56
The gene mutated in L-2-hydroxyglutaric aciduria encodes L-2-hydroxyglutarate dehydrogenase
2006
Rzem, R.; Van Schaftingen, E.; Veiga-da-Cunha, M.
Biochimie
88
113-116
The enzymology of 2-hydroxyglutarate, 2-hydroxyglutaramate and 2-hydroxysuccinamate and their relationship to oncometabolites
2017
Hariharan, V.A.; Denton, T.T.; Paraszcszak, S.; McEvoy, K.; Jeitner, T.M.; Krasnikov, B.F.; Cooper, A.J.
Biology
6
E24
Biochemical and epigenetic insights into L-2-hydroxyglutarate, a potential therapeutic target in renal cancer
2018
Shelar, S.; Shim, E.H.; Brinkley, G.J.; Kundu, A.; Carobbio, F.; Poston, T.; Tan, J.; Parekh, V.; Benson, D.; Crossman, D.K.; Buckhaults, P.J.; Rakheja, D.; Kirkman, R.; Sato, Y.; Ogawa, S.; Dutta, S.; Velu, S.E.; Emberley, E.; Pan, A.; Chen, J.; Huang, T.; Absher, D.; Becker, A.; Kunick, C.; Sudarshan, S.
Clin. Cancer Res.
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Identification of Escherichia coli YgaF as an L-2-hydroxyglutarate oxidase
2008
Kalliri, E.; Mulrooney, S.; Hausinger, R.
J. Bacteriol.
190
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L-2-hydroxyglutaric aciduria normal L-2-hydroxyglutarate dehydrogenase activity in liver from two new patients
1997
Wanders, R.
J. Inherit. Metab. Dis.
20
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Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate
2018
Knorr, S.; Sinn, M.; Galetskiy, D.; Williams, R.; Wang, C.; Mueller, N.; Mayans, O.; Schleheck, D.; Hartig, J.
Nat. Commun.
9
5071
Plants possess a cyclic mitochondrial metabolic pathway similar to the mammalian metabolic repair mechanism involving malate dehydrogenase and L-2-hydroxyglutarate dehydrogenase
2015
Huedig, M.; Maier, A.; Scherrers, I.; Seidel, L.; Jansen, E.E.; Mettler-Altmann, T.; Engqvist, M.K.; Maurino, V.G.
Plant Cell Physiol.
56
1820-1830
A gene encoding a putative FAD-dependent L-2-hydroxyglutarate dehydrogenase is mutated in L-2-hydroxyglutaric aciduria
2004
Rzem, R.; Veiga-da-Cunha, M.; Noel, G.; Goffette, S.; Nassogne, M.C.; Tabarki, B.; Schoeller, C.; Marquardt, T.; Vikkula, M.; Van Schaftingen, E.
Proc. Natl. Acad. Sci. USA
101
16849-16854
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The role of histone demethylase GASC1 in cancer and its therapeutic potential
2013
Holowatyj, A.; Yang, Z.
Curr. Cancer. Ther. Rev.
9
78-85
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