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BRENDA support

Ligand 8-hydroxy-6-mercaptopurine

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Basic Ligand Information

Molecular Structure
Picture of 8-hydroxy-6-mercaptopurine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H4N4OS
8-hydroxy-6-mercaptopurine
OIZCDCVIFRRJFF-UHFFFAOYSA-N
Synonyms:
6-mercapto-7,9-dihydropurin-8-one

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + 8-hydroxy-6-mercaptopurine = S-adenosyl-L-homocysteine + 8-hydroxy-6-methylmercaptopurine
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
6-mercaptopurine + H2O + O2 = 6-mercapto-7,9-dihydropurin-8-one + H2O2
show the reaction diagram
-

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0961
-
-

References & Links

Links to other databases for 8-hydroxy-6-mercaptopurine

ChEBI
PubChem
-
PubChem