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Ligand taxa-4(20),11-dien-5alpha,13alpha-diol Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C2 0 H3 2 O2
taxa-4(20),11-dien-5alpha,13alpha-diol
VTDWDDILICLAEK-IBVQPKKKSA-N
Show all BRENDA pathways known for taxa-4(20),11-dien-5alpha,13alpha-diol
Roles as Enzyme Ligand
Product in Enzyme-catalyzed Reactions (1 result)
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taxa-4(20),11-dien-5alpha-ol + [reduced NADPH-hemoprotein reductase] + O2 = taxa-4(20),11-dien-5alpha,13alpha-diol + [oxidized NADPH-hemoprotein reductase] + H2O
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Enzyme Kinetic Parameters
References & Links Literature References (2)
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Taxol biosynthesis: differential transformations of taxadien-5alpha-ol and its acetate ester by cytochrome P450 hydroxylases from Taxus suspension cells
2001
Wheeler, A.L.; Long, R.M.; Ketchum, R.E.B.; Rithner, C.D.; Williams, R.M.; Croteau, R.
Arch. Biochem. Biophys.
390
265-278
Taxol biosynthesis: taxane 13alpha-hydroxylase is a cytochrome P450-dependent monooxygenase
2001
Jennewein, S.; Rithner, C.D.; Williams, R.M.; Croteau, R.B.
Proc. Natl. Acad. Sci. USA
98
13595-13600
Links to other databases for taxa-4(20),11-dien-5alpha,13alpha-diol