Ligand pyocyanine

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Basic Ligand Information

Molecular Structure
Picture of pyocyanine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C13H10N2O
pyocyanine
YNCMLFHHXWETLD-UHFFFAOYSA-N
Synonyms:
pyocyanin, reduced pyocanine

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-methylphenazine-1-carboxylate + NADH + O2 = pyocyanin + NAD+ + CO2 + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-dehydro-D-gluconate + pyocyanine = 2,5-didehydro-D-gluconate + ?
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butyryl-CoA + pyocyanine + triphenyltetrazolium chloride = 2-butenoyl-CoA + reduced acceptor
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beta-(2-furyl)propionyl-CoA + pyocyanine = trans-beta-(2-furyl)acryloyl-CoA + reduced pyocanine
show the reaction diagram
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glycine + pyocyanine = HCN + ?
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pyocyanin + NADH + H = reduced pyocyanin + NAD+
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-methylphenazine-1-carboxylate + NADH + O2 = pyocyanin + NAD+ + CO2 + H2O
show the reaction diagram
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beta-(2-furyl)propionyl-CoA + pyocyanine = trans-beta-(2-furyl)acryloyl-CoA + reduced pyocanine
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
secondary metabolite, supports HCS mediated cyanide production
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
may decrease cellular catalase activity via both transcriptional regulation and direct inactivation of the enzyme
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inhibitory above 0.250 mM
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

References & Links

Links to other databases for pyocyanine

ChEBI
PubChem
ChEBI
PubChem