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Ligand 2-hydroxyphenazine Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 2 H8 N2 O
2-hydroxyphenazine
RETSEGNZNUBJRB-UHFFFAOYSA-N
reduced 2-hydroxyphenazine
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (4 results)
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H2 + 2-hydroxyphenazine = dihydro-2-hydroxyphenazine
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reduced coenzyme F420 + 2-hydroxyphenazine = ?
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oxidized coenzyme F420 + reduced 2-hydroxyphenazine = reduced coenzyme F420 + oxidized 2-hydroxyphenazine
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N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + reduced 2-hydroxyphenazine = coenzyme B + coenzyme M + 2-hydroxyphenazine
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Product in Enzyme-catalyzed Reactions (2 results)
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reduced coenzyme F420 + oxidized 2-hydroxyphenazine = oxidized coenzyme F420 + reduced 2-hydroxyphenazine
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N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + reduced 2-hydroxyphenazine = coenzyme B + coenzyme M + 2-hydroxyphenazine
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Enzyme Kinetic Parameters
KM Value (1 result)
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0.035
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at pH 7.0 and 25°C
References & Links Literature References (4)
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Isolation and characterization of methanophenazine and function of phenazines in membrane-bound electron transport of Methanosarcina mazei Go1
1998
Abken, H.J.; Tietze, M.; Brodersen, J.; Baumer, S.; Beifuss, U.; Deppenmeier, U.
J. Bacteriol.
180
2027-2032
Novel reactions involved in energy conservation by methanogenic archaea
1999
Deppenmeier, U.; Lienard, T.; Gottschalk, G.
FEBS Lett.
457
291-297
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The F420H2 heterodisulfide oxidoreductase system from Methanosarcina species. 2-Hydroxyphenazine mediates electron transfer from F420H2 dehydrogenase to heterodisulfide reductase
1998
Baeumer, S.; Murakami, E.; Brodersen, J.; Gottschalk, G.; Ragsdale, S.; Deppenmeier, U.
FEBS Lett.
428
295-298
Isolation and characterization of methanophenazine and function of phenazines in membrane-bound electron transport of Methanosarcina mazei Go1
1998
Abken, H.; Tietze, M.; Brodersen, J.; Baumer, S.; Beifuss, U.; Deppenmeier, U.
J. Bacteriol.
180
2027-2032
Links to other databases for 2-hydroxyphenazine
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