Ligand pheophorbide a

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Basic Ligand Information

Molecular Structure
Picture of pheophorbide a (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C35H36N4O5
pheophorbide a
NSFSLUUZQIAOOX-QEWKCGBTSA-N
Synonyms:
2-vinyl-4-ethyl chlorophyllide a, Pheophorbide

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
pheophorbide a + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = red chlorophyll catabolite + 2 oxidized ferredoxin [iron-sulfur] cluster
-
show the reaction diagram
pheophorbide a + H2O = pyropheophorbide a + methanol + CO2
-

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
2,4-divinyl chlorophyllide a + NADPH + H+ = 2-vinyl-4-ethyl chlorophyllide a + NADP+
-
show the reaction diagram
pheophytin a + H2O = phytol + pheophorbide
-

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
pheophorbide a + geranylgeranyl diphosphate = ?
-
show the reaction diagram
pheophorbide a + H2O = pyropheophorbide a + methanol + CO2
-

Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
2,4-divinyl chlorophyllide a + NADPH + H+ = 2-vinyl-4-ethyl chlorophyllide a + NADP+
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
stronger inhibitor than the corresponding Mg-chelate
-

Enzyme Kinetic Parameters

KM Value (8 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
pH 7.0, 24°C, recombinant enzyme
0.006
-
-
0.283
-
30°C, pH 7.0, Phedase type 1
0.0141
-
30°C, pH 7.0, Phedase type 2
0.0151
-
pH 7.0
0.0125
-
PPD type 1
0.0141
-
PPD type 2
0.0151
-
PPD-GST has about 6fold lower affinity for Pheid a than native PPDs
0.955
-

References & Links

Links to other databases for pheophorbide a

ChEBI
PubChem
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PubChem