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Ligand phosphatidyl-N-monomethylethanolamine

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.71

2 S-adenosyl-L-methionine + phosphatidyl-N-monomethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine

485554, 704482

-

2.1.1.71

S-adenosyl-L-methionine + phosphatidyl-N-monomethylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine

485554, 485555, 485166

-

2.1.1.71

2 entries

Product in Enzyme-catalyzed Reactions (1 result)

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Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.71

S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-monomethylethanolamine

0

-

Enzyme Kinetic Parameters

K_M Value (4 results)

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Show KM Value (4 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

2.1.1.71

0.054

-

-

485166

2.1.1.71

0.067

-

-

485560

2.1.1.71

0.08

-

-

485554

2.1.1.71

0.38

-

-

485166

2.1.1.71

4 entries

References & Links

Literature References (5)

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Show Reference (5 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

485166

2198947

Phosphatidylethanolamine methyltransferase and phospholipid methyltransferase activities from Saccharomyces cerevisiae. Enzymological and kinetic properties

1990

Gaynor, P.M.; Carman, G.M.

Biochim. Biophys. Acta

1045

156-163

485554

438165

Conversion of phosphatidylethanolamine to phosphatidylcholine in rat liver. Partial purification and characterization of the enzymatic activities

1979

Schneider, W.J.; Vance, D.E.

J. Biol. Chem.

254

3886-3891

485555

25437

Identification and properties of two methyltransferases in conversion of phosphatidylethanolamine to phosphatidylcholine

1978

Hirata, F.; Viveros, O.H.; Diliberto, E.J.; Axelrod, J.

Proc. Natl. Acad. Sci. USA

75

1718-1721

485560

7305396

Evidence for two methyltransferase involved in the conversion of phosphatidylethanolamine to phosphatidylcholine in the rat liver

1981

Sastry, B.V.R.; Statham, C.N.; Axelrod, J.; Hirata, F.

Arch. Biochem. Biophys.

211

762-773

704482

19366698

Functional characterization of phospholipid N-methyltransferases from Arabidopsis and soybean

2009

Keogh, M.R.; Courtney, P.D.; Kinney, A.J.; Dewey, R.E.

J. Biol. Chem.

284

15439-15447

Links to other databases for phosphatidyl-N-monomethylethanolamine

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Show Links (1 entry)