Ligand cytosine

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Basic Ligand Information

Molecular Structure
Picture of cytosine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H5N3O
cytosine
OPTASPLRGRRNAP-UHFFFAOYSA-N


Show all pahtways known for Show all BRENDA pathways known for cytosine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N3-methylcytosine + 2-oxoglutarate + O2 = cytosine + formaldehyde + succinate + CO2
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cytidine + H2O = D-ribose + cytosine
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Substrate in Enzyme-catalyzed Reactions (24 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cytosine + Br- + H2O2 = ?
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cytosine + D-ribose = cytidine + H2O
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cytosine + H2O = uracil + NH3
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cytosine + H2O = 6-hydroxy-1H-pyrimidin-2-one + NH3
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cytosine + H2O = ?
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Product in Enzyme-catalyzed Reactions (62 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cytidine + phosphate = cytosine + alpha-D-ribose 1-phosphate
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CMP + phosphate = cytosine + alpha-D-ribose 1,5-bisphosphate
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3'-CMP + thymidine = cytosine + TMP
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tRNA-C-C-A-Cn + H2O = tRNA-C-C-A-Cn-1 + cytosine
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3'-CMP + H2O = cytosine + phosphate
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CMP + H2O = cytosine + phosphate
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3'-CMP + H2O = cytosine + phosphate
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cytosine-mismatched double-stranded DNA + H2O = cytosine + double-stranded DNA with abasic site
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cytidine + H2O = cytosine + D-ribose
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3'-CMP + H2O = cytosine + phosphate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (10 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (25 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
2083
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pH 6.5, 40C

KM Value (50 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
4.7
-
-
0.62
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-
0.089
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-

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.286
-
-
0.17
-
-

References & Links

Links to other databases for cytosine

ChEBI
PubChem
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PubChem