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BRENDA support

Ligand D-homoserine

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Basic Ligand Information

Molecular Structure
Picture of D-homoserine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H9NO3
D-homoserine
UKAUYVFTDYCKQA-GSVOUGTGSA-N

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + D-homoserine = CoA + O-acetyl-D-homoserine
show the reaction diagram
-
succinyl-CoA + D-homoserine = CoA + O-succinyl-D-homoserine
show the reaction diagram
-
ATP + D-homoserine = ADP + O-phospho-D-homoserine
show the reaction diagram
-
D-homoserine = L-homoserine
show the reaction diagram
-
D-alanine + D-homoserine + ATP = D-alanyl-D-homoserine + ADP + phosphate
show the reaction diagram
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D-homoserine + ATP + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-oxo-4-hydroxybutyrate + isopropylamine = D-homoserine + acetone
show the reaction diagram
-
L-homoserine = D-homoserine
show the reaction diagram
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
12
-
recombinant protein
3.3
-
wild-type enzyme

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
10
-
recombinant protein
31.8
-
wild-type enzyme
25.1
-
pH 8.5, 37°C, recombinant enzyme

References & Links

Links to other databases for D-homoserine

ChEBI
PubChem
ChEBI
PubChem