Ligand glyceraldehyde

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Basic Ligand Information

Molecular Structure
Picture of glyceraldehyde (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H6O3
glyceraldehyde
MNQZXJOMYWMBOU-UHFFFAOYSA-N
Synonyms:
(R,S)-glyceraldehyde, 2,3-dihydroxypropanal, 2,3-dihydroxypropanaldehyde, an aldose, D,L-glyceraldehyde, DL-glyceraldehyde, glyceral


Show all pahtways known for Show all BRENDA pathways known for glyceraldehyde

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
DL-glyceraldehyde + NADPH + H+ = DL-glycerol + NADP+
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glyceraldehyde + NAD(P)H = glycerol + NAD(P)+
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glyceraldehyde + NAD+ + H2O = ?
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glyceraldehyde + H2O + oxidized ferredoxin = glycerate + H+ + reduced ferredoxin
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In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glycerol + NAD+ = glyceraldehyde + NADH + H+
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-
-
glycerol + O2 = glyceraldehyde + H2O2
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-
-
glycerol + O2 = glyceraldehyde + H2O2
show the reaction diagram
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-

Substrate in Enzyme-catalyzed Reactions (96 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
DL-glyceraldehyde + H+ = glycerol + NAD+
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DL-glyceraldehyde + NADPH = dihydroxyacetone + NADP+
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DL-glyceraldehyde + NADH = glycerol + NAD+
show the reaction diagram
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DL-glyceraldehyde + NADPH = glycerol + NADP+
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glyceraldehyde + NADPH + H+ = ?
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DL-glyceraldehyde + NADPH = DL-glycerol + NADP+
show the reaction diagram
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DL-glyceraldehyde + NADPH + H+ = ?
show the reaction diagram
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DL-glyceraldehyde + NADPH + H+ = glycerol + NADP+
show the reaction diagram
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glyceraldehyde + NADPH = ?
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glyceraldehyde + NADH + H+ = ? + NAD+
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glyceraldehyde + NAD(P)H = glycerol + NAD(P)+
show the reaction diagram
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DL-glyceraldehyde + NADPH + H+ = glycerol + NADP+
show the reaction diagram
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DL-glyceraldehyde + NADPH = glycerol + NADP+
show the reaction diagram
-
DL-glyceraldehyde + NADPH + H+ = ?
show the reaction diagram
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DL-glyceraldehyde + NADPH + H+ = ?
show the reaction diagram
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DL-glyceraldehyde + NADPH + H+ = glycerol + NADP+
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glyceraldehyde + NADH + H+ = ?
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glyceraldehyde + phenazine methosulfate = ? + reduced phenazine methosulfate
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glyceraldehyde + O2 = ? + H2O2
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DL-glyceraldehyde + acceptor = ? + reduced acceptor
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DL-glyceraldehyde + nitro blue tetrazolium = ? + reduced nitro blue tetrazolium
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DL-Glyceraldehyde + D-fructose = ?
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glyceraldehyde + 2,6-dichloroindophenol + H2O = ?
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DL-glyceraldehyde + NAD+ + H2O = glycerate + NADH
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DL-glyceraldehyde + NAD+ + H2O = 2,3-dihydroxypropanoic acid + NADH + H+
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DL-glyceraldehyde + NAD+ + H2O = glycerate + NADH
show the reaction diagram
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glyceraldehyde + NAD+ + H2O = glycerate + NADH
show the reaction diagram
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DL-glyceraldehyde + NADP+ + H2O = glycerate + NADPH + H+
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glyceraldehyde + NAD+ + H2O = ?
show the reaction diagram
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DL-glyceraldehyde + NAD+ + H2O = DL-glycerate + NADH + H+
show the reaction diagram
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glyceraldehyde + NAD+ + H2O = glycerate + NADH + H+
show the reaction diagram
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DL-glyceraldehyde + H2O + O2 = ?
show the reaction diagram
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glyceraldehyde + H2O + oxidized ferredoxin = glycerate + H+ + reduced ferredoxin
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DL-glyceraldehyde + 2,6-dichlorophenolindophenol + H2O = glycerate + reduced 2,6-dichlorophenolindophenol
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DL-glyceraldehyde + NADPH = ?
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dihydroxypropanone + DL-glyceraldehyde = D-fructose
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2,3-dihydroxypropanaldehyde + (S)-(-)-1-phenylethylamine = ?
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ATP + glyceraldehyde = ADP + D-glyceraldehyde-3-phosphate
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glyceraldehyde = ?
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pyruvate + glyceraldehyde = ?
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D-ribulose 5-phosphate + DL-glyceraldehyde = ?
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pyruvate + DL-glyceraldehyde = ?
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pyruvate + (R,S)-glyceraldehyde = ?
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Product in Enzyme-catalyzed Reactions (16 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glycerol + NADP+ = DL-glyceraldehyde + NADPH + H+
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glycerol + NAD+ = glyceraldehyde + NADH + H+
show the reaction diagram
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glycerol + NAD+ = DL-glyceraldehyde + NADH
show the reaction diagram
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glycerol + NADP+ = glyceraldehyde + NADPH + H+
show the reaction diagram
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glycerol + NADP+ = glyceraldehyde + NADPH + H+
show the reaction diagram
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glycerol + NAD+ = DL-glyceraldehyde + NADH
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glycerol + O2 = glyceraldehyde + H2O2
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glycerol + O2 = glyceraldehyde + H2O2
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glycerol + O2 = glyceraldehyde + H2O2
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glycerol + ferrocyanide = 2,3-dihydroxypropanal + ferricyanide
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glyceraldehyde-3-phosphate + H2O = glyceraldehyde + phosphate
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glyceraldehyde 3-phosphate + H2O = glyceraldehyde + phosphate
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2-dehydro-3-deoxy-D-gluconate = pyruvate + glyceraldehyde
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D-glucosaminate = pyruvate + glyceraldehyde + NH3
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Inhibitor in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibition
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substrate inhibition
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substrate inhibition
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1 mM causes 7% inhibition at 30°C
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competitive
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non competitive, 10 mM
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competitive
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13% inhibition at 4 mM
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0% residual activity at 10 mM
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about 60% inhibition at 10 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (40 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.215
-
+/-0.3
0.52
-
1 mM
4.35
-
recombinant enzyme, in 50 mM Tricine buffer (pH 8.5), at 25°C
4.8
-
pH 7.5, 70°C
2.8
-
pH 8.4, 45°C, benzyl viologen as electron acceptor
10.5
-
with benzyl viologen as cosubstrate, at 45°C
0.54
-
mutant F178, pH 8.5, 30°C
5.17
-
pH 7.5, 30°C
5.6
-
Kcat(app) with pyruvate as carbonyl donor, pH 8.0 and 25°C
5.6
-
pH 8.0, 25°C

KM Value (128 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
120
-
-
0.83
-
-
1.671
-
-
0.56
-
1 mM
6
-
in 100 mM sodium phosphate (pH 7.0), at 22°C
7.5
-
-
0.31
-
37°C, pH 7.0
0.09
-
80°C, pH 6.7
10
-
-
120
-
mutant F178, pH 8.5, 30°C
0.01
-
pH 7.0, 22°C
0.042
-
70°C, pH 8.0
88.6
-
Km(app) with pyruvate as carbonyl donor, pH 8.0 and 25°C
88.6
-
pH 8.0, 25°C

Ki Value (6 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
7.4
-
-
1.05
-
-
19
20
pH 7.9, 20°C
0.01
-
direction of aldol condensation, pH not specified in the publication, temperature not specified in the publication

References & Links

Links to other databases for glyceraldehyde

ChEBI
PubChem
ChEBI
PubChem