Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
GDP-mannose + pyridylaminated Man9GlcNAc2 = GDP + pyridylaminated Man10GlcNAc2
-
Manalpha(1->2)Manalpha(1->2)Manalpha(1->3)[Manalpha(1->2)Manalpha(1->6)[Manalpha(1->2)Manalpha(1->3)]Manalpha(1->6)]Manbeta(1->4)GlcNAcbeta(1->4)GlcNAcbeta-2-pyridylamine + H2O = Manalpha(1->2)Manalpha(1->3)[Manalpha(1->2)Manalpha(1->6)[Manalpha(1->2)Manalpha(1->3)]Manalpha(1->6)]Manbeta(1->4)GlcNAcbeta(1->4)GlcNAcbeta-2-pyridylamine + D-mannose
-
alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-alpha-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-2-pyridylamine + 3 H2O = alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-alpha-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-2-pyridylamine + 3 D-mannopyranose
-
alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-alpha-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-2-pyridylamine + H2O = alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-alpha-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-2-pyridylamine + D-mannopyranose
-
Manalpha(1->2)Manalpha(1->2)Manalpha(1->3)[Manalpha(1->2)Manalpha(1->6)[Manalpha(1->2)Manalpha(1->3)]Manalpha(1->6)]Manbeta(1->4)GlcNAcbeta(1->4)GlcNAcbeta-2-pyridylamine + H2O = Manalpha(1->2)Manalpha(1->3)[Manalpha(1->2)Manalpha(1->6)[Manalpha(1->2)Manalpha(1->3)]Manalpha(1->6)]Manbeta(1->4)GlcNAcbeta(1->4)GlcNAcbeta-2-pyridylamine + D-mannose
-
pyridylaminated Man9GlcNAc2 + H2O = pyridylaminated Man8GlcNAc2 + D-mannose
-
6 pyridylamino-Man9GlcNAc2 + H2O = pyridylamino-Man8GlcNAc2 + pyridylamino-Man7GlcNAc2 + pyridylamino-Man6GlcNAc2 + pyridylamino-Man5GlcNAc2 + pyridylamino-Man4GlcNAc2 + pyridylamino-Man3GlcNAc2 + 21 alpha-D-mannopyranose
-
pyridylamino-Man9GlcNAc2 + H2O = pyridylamino-Man8GlcNAc2 + alpha-D-mannopyranose
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.000026
-
37°C, pH 6.7, pyridylamine-tagged Man9GlcNAc2, mutant enzyme E599Q
0.000027
-
37°C, pH 6.6, pyridylamine-tagged Man9GlcNAc2, mutant enzyme D463N/E599Q
0.00028
-
37°C, pH 6.6, pyridylamine-tagged Man9GlcNAc2, mutant enzyme E330Q/E599Q
0.0046
-
37°C, pH 6.8, pyridylamine-tagged Man9GlcNAc2, mutant enzyme D463N
0.018
-
37°C, pH 7.1, pyridylamine-tagged Man9GlcNAc2, mutant enzyme E330Q
0.03
-
37°C, pH 6.8, mutant enzyme F659A
0.06
-
37°C, pH 6.5, mutant enzyme T688A
0.07
-
37°C, pH 6.5, mutant enzyme R461L
0.084
-
37°C, pH 5.3, mutant enzyme E330Q
0.084
-
37°C, pH 5.3, pyridylamine-tagged Man9GlcNAc2, mutant enzyme E330Q
0.11
-
37°C, pH 6.5, mutant enzyme R597A
0.6
-
37°C, pH 6.5, mutant enzyme R461A
0.86
-
37°C, pH 6.9, pyridylamine-tagged Man9GlcNAc2, mutant enzyme H524A
3.7
-
37°C, pH 7.0, wild-type enzyme
3.7
-
37°C, pH 7.1, pyridylamine-tagged Man9GlcNAc2, wild-type enzyme
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.015
-
37°C, pH 6.5, mutant enzyme T688A
0.068
-
37°C, pH 5.3, mutant enzyme E330Q
0.068
-
37°C, pH 5.3, pyridylamine-tagged Man9GlcNAc2, mutant enzyme E330Q
0.09
-
37°C, pH 7.1, pyridylamine-tagged Man9GlcNAc2, mutant enzyme E330Q
0.11
-
37°C, pH 6.8, pyridylamine-tagged Man9GlcNAc2, mutant enzyme D463N
0.11
-
37°C, pH 7.0, wild-type enzyme
0.11
-
37°C, pH 7.1, pyridylamine-tagged Man9GlcNAc2, wild-type enzyme
0.12
-
37°C, pH 6.8, mutant enzyme F659A
0.15
-
37°C, pH 6.6, pyridylamine-tagged Man9GlcNAc2, mutant enzyme E330Q/E599Q
0.16
-
37°C, pH 6.7, pyridylamine-tagged Man9GlcNAc2, mutant enzyme E599Q
0.21
-
37°C, pH 6.9, pyridylamine-tagged Man9GlcNAc2, mutant enzyme H524A
0.26
-
37°C, pH 6.6, pyridylamine-tagged Man9GlcNAc2, mutant enzyme D463N/E599Q
0.33
-
37°C, pH 6.5, mutant enzyme R461L
0.47
-
37°C, pH 6.5, mutant enzyme R597A
0.51
-
37°C, pH 6.5, mutant enzyme R461A
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Purification and properties of major alpha-D-mannosidase in the luminal fluid of porcine epididymis
1999
Jin, Y.Z.; Dacheux, F.; Dacheux, J.L.; Bannai, S.; Sugita, Y.; Okamura, N.
Biochim. Biophys. Acta
1432
382-392
Cloning, expression, purification, and characterization of the murine lysosomal acid alpha-mannosidase
1997
Merkle, R.K.; Zhang, Y.; Ruest, P.J.; Lal, A.; Liao, Y.F.; Moremen, K.W.
Biochim. Biophys. Acta
1336
132-146
Cloning, expression, purification, and characterization of the human broad specificity lysosomal acid alpha-mannosidase
1996
Liao, Y.F.; Lal, A.; Moremen, K.W.
J. Biol. Chem.
271
28348-28358
Purification and characterization of hen oviduct alpha 1,2-mannosidase
1996
Hamagashira, N.; Oku, H.; Mega, T.; Hase, S.
J. Biochem.
119
998-1003
Filamentous fungus Aspergillus oryzae has two types of alpha-1,2-mannosidases, one of which is a microsomal enzyme that removes a single mannose residue from Man9GlcNAc2
2001
Yoshida, T.; Kato, Y.; Asada, Y.; Nakajima, T.
Glycoconj. J.
17
745-748
Schizosaccharomyces pombe och1+ encodes alpha-1,6-mannosyltransferase that is involved in outer chain elongation of N-linked oligosaccharides
2001
Yoko-o, T.; Tsukahara, K.; Watanabe, T.; Hata-Sugi, N.; Yoshimatsu, K.; Nagasu, T.; Jigami, Y.
FEBS Lett.
489
75-80
Mechanism of class 1 (glycosylhydrolase family 47) alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control
2005
Karaveg, K.; Siriwardena, A.; Tempel, W.; Liu, Z.; Glushka, J.; Wang, B.; Moremen, K.W.
J. Biol. Chem.
280
16197-16207
Energetics of substrate binding and catalysis by class 1 (glycosylhydrolase family 47) alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control
2005
Karaveg, K.; Moremen, K.W.
J. Biol. Chem.
280
29837-29848
Improved expression and characterization of recombinant human Golgi alpha1,2-mannosidase I isoforms (IA2 and IC) by Escherichia coli
2011
Isoyama-Tanaka, J.; Dohi, K.; Misaki, R.; Fujiyama, K.
J. Biosci. Bioeng.
112
14-19
Purification and biochemical characterisation of endoplasmic reticulum alpha1,2-mannosidase from Sporothrix schenckii
2010
Mora-Montes, H.M.; Robledo-Ortiz, C.I.; Gonzalez-Sanchez, L.C.; Lopez-Esparza, A.; Lopez-Romero, E.; Flores-Carreon, A.
Mem. Inst. Oswaldo Cruz
105
79-85