Ligand heme

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Basic Ligand Information

Molecular Structure
Picture of heme (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C34H34FeN4O4
heme
KABFMIBPWCXCRK-RGGAHWMASA-L
Synonyms:
Fe-protoporphyrin complex, Fe-protoporphyrin IX, Fe2+-protoporphyrin, ferriprotoporphorin IX, ferriprotoporphyrin IX, ferroheme b, ferroprotoporphyrin IX, Haemin, heme b, heme b556, heme b562, heme[side 1], heme[side 2], hemin, mesoheme IX, protoheme, protoheme IX


Show all pahtways known for Show all BRENDA pathways known for heme

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (73 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 S-adenosyl-L-methionine + protoheme + 2 reduced flavodoxin = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + anaerobilin + Fe2+ + 2 oxidized flavodoxin
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ferriprotoporphyrin IX = beta-hematin
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ATP + H2O + heme[side 1] = ADP + phosphate + heme[side 2]
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In Vivo Product in Enzyme-catalyzed Reactions (37 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + heme[side 1] = ADP + phosphate + heme[side 2]
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (172 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
hemin + O2 = ?
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apocytochrome c1 + heme = holocytochrome c1
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ATP + H2O + heme[side 1] = ADP + phosphate + heme[side 2]
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Product in Enzyme-catalyzed Reactions (99 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + heme[side 1] = ADP + phosphate + heme[side 2]
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Enzyme Cofactor/Cosubstrate (16262 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
heme/iron-sulfur protein. The heme groups of the enzyme are rapidly reduced by reduced 2,3-dimethyl-1,4-naphthoquinone, which indicates that the enzyme functions as a menaquinol-acceptor oxidoreductase
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