Ligand 3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose

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Basic Ligand Information

Molecular Structure
Picture of 3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H22O11
3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose
QIGJYVCQYDKYDW-LBGGPIGOSA-N
Synonyms:
(alpha-D-mannopyranosyl)-(1->3)-alpha-D-mannopyranoside, 1,3-alpha-D-mannobiose, 3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranoside, alpha-(1,3)-D-mannobiose, alpha-(1-3)-mannobiose, alpha-(1->3)-D-mannobiose, alpha-1,3-mannobiose, alpha-D-1,3-mannopyranosyl-alpha-D-mannopyranose, alpha-D-Manp-(1,3)-D-Manp, D-mannosyl-alpha-(1,3)-D-mannose, Man-alpha(1-3)Man, Manalpha(1-3)Man, Manalpha1-3Man
Pathway Source
Pathways


Show all pahtways known for Show all BRENDA pathways known for 3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose + H2O = alpha-D-mannopyranose
show the reaction diagram
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alpha-(1-3)-mannobiose + H2O = alpha-D-mannopyranose + D-mannopyranose
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-N-acetyl-D-glucosamine + Manalpha(1-3)Man = UDP + ?
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UDP-D-xylose + D-mannosyl-alpha-(1,3)-D-mannose = UDP + D-xylosyl-beta-(1,2)-D-mannosyl-alpha-(1,3)-D-mannose
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UDP-xylose + 3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose = UMP + 3-O-(6-O-alpha-D-xylosylphosphono-alpha-D-mannopyranosyl)-alpha-D-mannopyranose
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
methyl alpha-D-mannopyranosyl-(1->3)-alpha-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->2)-alpha-D-mannopyranoside + H2O = alpha-(1->3)-D-mannobiose + methyl alpha-(1->2)-D-mannobioside + ?
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
in decreasing order of efficiency: alpha1,2, alpha 1,3 and alpha1,6-mannosylmannose
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50% inhibition at 18 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
6.4
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pH 6.8, 37C, recombinant enzyme

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose

ChEBI
PubChem
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PubChem