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Ligand 7,8-dihydromethanopterin

Basic Ligand Information

Molecular Structure

Show all BRENDA pathways known for 7,8-dihydromethanopterin

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

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Show Natural Substrate (4 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.5.1.47

7,8-dihydromethanopterin + NAD(P)H + H+ = 5,6,7,8-tetrahydromethanopterin + NAD(P)+

719701

-

1.5.99.15

7,8-dihydromethanopterin + FMNH2 = 5,6,7,8-tetrahydromethanopterin + FMN

742870

-

1.5.99.15

7,8-dihydromethanopterin + reduced acceptor = 5,6,7,8-tetrahydromethanopterin + oxidized acceptor

727782

-

1.5.99.15

7,8-dihydromethanopterin + reduced ferredoxin = 5,6,7,8-tetrahydromethanopterin + ferredoxin

742781

-

1.5.99.15

3 entries

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.5.99.15

5,6,7,8-tetrahydromethanopterin + oxidized acceptor = 7,8-dihydromethanopterin + reduced acceptor

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Substrate in Enzyme-catalyzed Reactions (5 results)

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Show Substrate (5 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.5.1.47

7,8-dihydromethanopterin + NAD(P)H + H+ = 5,6,7,8-tetrahydromethanopterin + NAD(P)+

719701

-

1.5.99.15

7,8-dihydromethanopterin + FMNH2 = 5,6,7,8-tetrahydromethanopterin + FMN

742870

-

1.5.99.15

7,8-dihydromethanopterin + reduced acceptor = 5,6,7,8-tetrahydromethanopterin + oxidized acceptor

727782

-

1.5.99.15

7,8-dihydromethanopterin + reduced dithiothreitol = 5,6,7,8-tetrahydromethanopterin + oxidized dithiothreitol

727782

-

1.5.99.15

7,8-dihydromethanopterin + reduced ferredoxin = 5,6,7,8-tetrahydromethanopterin + ferredoxin

742781

-

1.5.99.15

4 entries

Product in Enzyme-catalyzed Reactions (1 result)

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Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.5.99.15

5,6,7,8-tetrahydromethanopterin + oxidized acceptor = 7,8-dihydromethanopterin + reduced acceptor

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-

Enzyme Kinetic Parameters

References & Links

Literature References (4)

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Show Reference (4 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

719701

15028691

Biochemical characterization of a dihydromethanopterin reductase involved in tetrahydromethanopterin biosynthesis in Methylobacterium extorquens AM1

2004

Caccamo, M.A.; Malone, C.S.; Rasche, M.E.

J. Bacteriol.

186

2068-2073

727782

23995635

Discovery and characterization of the first archaeal dihydromethanopterin reductase, an iron-sulfur flavoprotein from Methanosarcina mazei

2014

Wang, S.; Tiongson, J.; Rasche, M.E.

J. Bacteriol.

196

203-209

742781

23995635

Discovery and characterization of the first archaeal dihydromethanopterin reductase, an iron-sulfur flavoprotein from Methanosarcina mazei

2014

Wang, S.; Tiongson, J.; Rasche, M.E.

J. Bacteriol.

196

203-209

742870

24523405

Structure of dihydromethanopterin reductase, a cubic protein cage for redox transfer

2014

McNamara, D.E.; Cascio, D.; Jorda, J.; Bustos, C.; Wang, T.C.; Rasche, M.E.; Yeates, T.O.; Bobik, T.A.

J. Biol. Chem.

289

8852-8864

Links to other databases for 7,8-dihydromethanopterin

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Show Links (1 entry)

ChEBI

PubChem

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