Ligand 6-hydroxymethyl-7,8-dihydropterin diphosphate

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Basic Ligand Information

Molecular Structure
Picture of 6-hydroxymethyl-7,8-dihydropterin diphosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H11N5O8P2
6-hydroxymethyl-7,8-dihydropterin diphosphate
FCQGJGLSOWZZON-UHFFFAOYSA-N
Synonyms:
(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate, (7,8-dihydropterin-6-yl)methyl diphosphate, 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate, 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine, 6-hydroxymethyl-7,8-dihydropterin-diphosphate, 6-hydroxymethyl-7,8-dihydropterine diphosphate, 6-hydroxymethyldihydropteridine diphosphate


Show all pahtways known for Show all BRENDA pathways known for 6-hydroxymethyl-7,8-dihydropterin diphosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-(beta-D-ribofuranosyl)aniline 5'-phosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (20 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibitor of ATP, mixed type inhibitor of 6-hydroxymethyl-7,8-dihydropteridine
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 6-hydroxymethyl-7,8-dihydropterin diphosphate

ChEBI
PubChem
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PubChem