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Ligand phosphonic acid analog of ADP

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Basic Ligand Information

Molecular Structure
Picture of phosphonic acid analog of ADP (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C11H17N5O9P2
phosphonic acid analog of ADP
OLCWZBFDIYXLAA-IOSLPCCCSA-N
Synonyms:
5'-adenylylmethylene diphosphonate, adenosine 5'-(alpha,beta-methylene)diphosphate, adenosine 5'-methylene diphosphate, adenosine 5'-methylene diphosphonate, adenyl-5'-yl methylene diphosphonate, adenyl-5'-yl methylene monophosphonate, adenylomethyloendiphosphate, adenylyl methylenediphosphate, adenylylmethylenediphosphate, alpha,beta-metADP, alpha,beta-methylene-adenosine 5'-diphosphate, alpha,beta-methylene-adenosine diphosphate, alpha,beta-methylene-ADP, alpha,beta-methylene adenosine-5'-diphosphate, alpha,beta-methyleneadenosine 5'-diphosphate, alpha,beta-methylene adenosine 5'-diphosphate, alpha,beta-methylene adenosine diphosphate, alpha,beta-methylene ADP, alpha-beta-methylene-ADP, alpha/beta-methylene-ADP, alphabeta-methylene ADP

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + adenosine 5'-methylene diphosphonate = ADP + ?
show the reaction diagram
-
adenylomethyloendiphosphate = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 alpha,beta-methylene-ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O = 2 alpha,beta-methylene-ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
allosteric activator, can replace ADP, with 66% efficiency with bovine serum albumin as substrate
-

Inhibitor in Enzyme-catalyzed Reactions (91 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive to ATP
-
i.e. AMP-CP, ATP analogue
-
i.e. AMP-PCP
-

3D Structure of Enzyme-Ligand-Complex (PDB) (99 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

Ki Value (9 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0021
-
pH 6.8

References & Links

Links to other databases for phosphonic acid analog of ADP

ChEBI
PubChem
ChEBI
PubChem