Ligand cholestanol

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Basic Ligand Information

Molecular Structure
Picture of cholestanol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C27H48O
cholestanol
QYIXCDOBOSTCEI-QCYZZNICSA-N
Synonyms:
3-betacholestanol, 5alpha-Cholestan-3beta-ol, beta-cholestanol, dihydrocholesterol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
beta-cholestanol + O2 = ?
show the reaction diagram
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5alpha-cholestan-3beta-ol + ferrocytochrome b5 + H+ + O2 = cholest-5-en-3beta-ol + ferricytochrome b5 + 2 H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (16 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5alpha-cholestan-3beta-ol + NADPH + O2 = 5alpha-cholestan-3beta,7alpha-diol + NADP+ + H2O
show the reaction diagram
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5alpha-cholestan-3beta-ol + ferrocytochrome b5 + H+ + O2 = cholest-5-en-3beta-ol + ferricytochrome b5 + 2 H2O
show the reaction diagram
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cholestanol + NADPH + H+ + O2 = 22-hydroxy-cholestanol + NADP+ + H2O
show the reaction diagram
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oleoyl-CoA + cholestanol = CoA + cholestanyl oleate
show the reaction diagram
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tripalmitoylglycerol + 5alpha-cholestan-3beta-ol = ?
show the reaction diagram
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UDPglucose + 5alpha-cholestan-3beta-ol = UDP + 5alpha-cholestan-3beta-ol 3-O-beta-D-glucoside
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cholestanone + NADPH = cholestanol + NADP+
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.063
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References & Links

Links to other databases for cholestanol

ChEBI
PubChem
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PubChem