Ligand androstenediol

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Basic Ligand Information

Molecular Structure
Picture of androstenediol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C19H30O2
androstenediol
QADHLRWLCPCEKT-LOVVWNRFSA-N
Synonyms:
(3beta,17beta)-androst-5-ene-3,17-diol, 3beta,17beta-dihydroxyandrost-5-ene, 5-androsten-3beta,17beta-diol, 5-androstene-3beta,17beta-diol, androst-5-en-3beta,17beta-diol, androst-5-ene-3beta,17beta-diol, androstendiol, androstene diol

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-androstene-3beta,17beta-diol + NADP+ = ?
show the reaction diagram
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5-androstene-3beta,17beta-diol + NADP+ = ? + NADPH
show the reaction diagram
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androst-5-ene-3beta,17beta-diol + NAD+ = androst-5-ene-3beta-ol-17-one + NADH
show the reaction diagram
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5-androstene-3beta,17beta-diol + O2 = 5-androsten-17beta-ol-3-one + H2O2
show the reaction diagram
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androstenediol + NADPH = 5alpha-androstan-3beta,17beta-diol + NADP+
show the reaction diagram
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3'-phosphoadenylylsulfate + androstenediol = adenosine 3',5'-bisphosphate + androstenediol sulfate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
androstene oxide + H2O = androstene diol
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.0333
-
-
0.1
-
at pH 7.4 and 37°C
0.043
-
pH 7.4, 25°C, recombinant enzyme

KM Value (9 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.001
-
-
0.0031
-
at pH 7.4 and 37°C
0.0033
-
pH 7.4, 25°C, recombinant enzyme
0.012
-
pH 7.5, 25°C, BNST4

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.035
-
pH 8.1, 37°C

References & Links

Links to other databases for androstenediol

ChEBI
PubChem
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PubChem