Ligand isomaltose

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Basic Ligand Information

Molecular Structure
Picture of isomaltose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H22O11
isomaltose
DLRVVLDZNNYCBX-NCFXGAEVSA-N
Synonyms:
alpha-D-glucopyranosyl-(1-6)-alpha-D-glucopyranoside

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
isomaltose + H2O = D-glucose
show the reaction diagram
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isomaltose + H2O = beta-D-glucose + D-glucose
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isomaltose = isomaltooligosaccharide
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isomaltose + H2O = glucose
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isomaltose + H2O = 2 D-glucose
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In Vivo Product in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
maltotriose + H2O = isomaltose + isopanose + panose + branched glucooligosaccharides
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glucooligosaccharides + H2O = isomaltose + D-glucose
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Substrate in Enzyme-catalyzed Reactions (48 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
isomaltose + 2,6-dichlorophenolindophenol = 6-O-alpha-D-xylo-hexopyranosyl-4-ulose-alpha-D-glucopyranose + reduced 2,6-dichlorophenolindophenol
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acetyl-CoA + isomaltose = CoA + 6-O-(6-O-acetyl-alpha-D-glucopyranosyl)-D-glucopyranose
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isomaltose + alpha-D-glucose 1-phosphate = ?
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isomaltose = D-glucose
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starch + isomaltose = ?
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beta-D-glucose-1-phosphate + isomaltose = 6-O-alpha-D-glucopyranosyl trehalose + phosphate
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isomaltose + H2O = ?
show the reaction diagram
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isomaltose + H2O = ?
show the reaction diagram
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isomaltose + H2O = ?
show the reaction diagram
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isomaltose + H2O = beta-D-glucose + D-glucose
show the reaction diagram
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isomaltose + H2O = ?
show the reaction diagram
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isomaltose + H2O = alpha-D-glucopyranose
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (57 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
starch + D-glucose = maltose + isomaltose
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sucrose + D-glucose = D-fructose + isomalto-oligosaccharide + isomaltose + leucrose
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maltotriose + H2O = isomaltose + isopanose + panose + branched glucooligosaccharides
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pullulan + H2O = isomaltose
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glucan + H2O = isomaltose + nigerose + nigerotriose + oligosaccharides
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D(+)-raffinose + H2O = beta-D-fructose + alpha-D-glucopyranosyl-(1-6)-alpha-D-glucopyranoside
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4-nitrophenyl-alpha-isomaltoside + H2O = 4-nitrophenol + isomaltose
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
lowering Km, 142% activation at 50 mM
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Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
hydrolysis of p-nitrophenyl-alpha-D-glucopyranoside, competitive
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competitive inhibition
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10 mM, 0.4% amylose, relative activity 82%
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (44 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.9
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enzyme assay at 37C in 50 mM Tris/HCl (pH 7.0)
11.4
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pH 6.0, 35C

KM Value (89 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
71
-
enzyme assay at 37C in 50 mM Tris/HCl (pH 7.0)
4.54
-
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2.38
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pH 6.0, 35C

Ki Value (4 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.3
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References & Links

Links to other databases for isomaltose

ChEBI
PubChem
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PubChem