Ligand 5,10-methylenetetrahydromethanopterin

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Basic Ligand Information

Molecular Structure
Picture of 5,10-methylenetetrahydromethanopterin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C31H45N6O16P
5,10-methylenetetrahydromethanopterin
GBMIGEWJAPFSQI-CAFBYHECSA-N
Synonyms:
methylenetetrahydromethanopterin, N5,N10-methylenetetrahydromethanopterin

Show all pahtways known for Show all BRENDA pathways known for 5,10-methylenetetrahydromethanopterin

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420 = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5,10-methenyltetrahydromethanopterin + H2 = 5,10-methylenetetrahydromethanopterin + H+
show the reaction diagram
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5,10-methenyltetrahydromethanopterin + reduced coenzyme F420 = 5,10-methylenetetrahydromethanopterin + coenzyme F420
show the reaction diagram
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5,6,7,8-tetrahydromethanopterin + formaldehyde = 5,10-methylenetetrahydromethanopterin + H2O
show the reaction diagram
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5,6,7,8-tetrahydromethanopterin + formaldehyde = 5,10-methylenetetrahydromethanopterin + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420 = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5,10-methenyltetrahydromethanopterin + H2 = 5,10-methylenetetrahydromethanopterin + H+
show the reaction diagram
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H2 + methenyltetrahydromethanopterin = H+ + methylenetetrahydromethanopterin
show the reaction diagram
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5,10-methenyltetrahydromethanopterin + reduced coenzyme F420 = 5,10-methylenetetrahydromethanopterin + coenzyme F420
show the reaction diagram
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-
5,6,7,8-tetrahydromethanopterin + formaldehyde = 5,10-methylenetetrahydromethanopterin + H2O
show the reaction diagram
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-
5,6,7,8-tetrahydromethanopterin + formaldehyde = 5,10-methylenetetrahydromethanopterin + H2O
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1462
-
pH 6.5, 60°C
275
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65°C, pH 6.8

KM Value (26 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.01
-
at pH 6.0 and 25°C

References & Links

Links to other databases for 5,10-methylenetetrahydromethanopterin

ChEBI
PubChem
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PubChem