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Ligand 4-(2-aminophenyl)-2,4-dioxobutanoate

Basic Ligand Information

Molecular Structure

Show all BRENDA pathways known for 4-(2-aminophenyl)-2,4-dioxobutanoate

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Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

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Show Natural Product (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.6.1.63

L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

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2.6.1.7

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate + H2O

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Product in Enzyme-catalyzed Reactions (25 results)

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Show Product (25 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.4.99.6

D-kynurenine + H2O + 2,6-dichlorophenolindophenol = 4-(2-aminophenyl)-2,4-dioxobutanoate + NH3 + reduced 2,6-dichlorophenolindophenol

394974

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1.4.99.6

D-kynurenine + H2O + methylene blue = 4-(2-aminophenyl)-2,4-dioxobutanoate + NH3 + reduced methylene blue

394974

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1.4.99.6

2 entries

2.6.1.44

kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

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2.6.1.57

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate

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2.6.1.63

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate

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2.6.1.63

L-kynurenine + 4-methylsulfanyl-2-oxobutanoate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-methionine

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2.6.1.63

L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

636995,

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2.6.1.63

L-kynurenine + hydroxypyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-serine

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2.6.1.63

L-kynurenine + pyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine

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2.6.1.63

5 entries

2.6.1.64

L-kynurenine + pyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine

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2.6.1.7

L-kynurenine + 2-oxobutanoate = 4-(2-aminophenyl)-2,4-dioxobutanoate + 2-aminobutanoate

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2.6.1.7

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate

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2.6.1.7

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate + H2O

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2.6.1.7

L-kynurenine + 2-oxoisocaproate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-leucine

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2.6.1.7

L-kynurenine + 2-oxoisocaproic acid = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-leucine

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2.6.1.7

L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

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2.6.1.7

L-kynurenine + mercaptopyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-cysteine

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2.6.1.7

L-kynurenine + oxaloacetate = 4-(2-aminophenyl)-2,4-dioxobutanoate + 2-aminosuccinate

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2.6.1.7

L-kynurenine + oxaloacetate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate

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2.6.1.7

L-kynurenine + phenylpyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-phenylalanine

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2.6.1.7

L-kynurenine + pyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine

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2.6.1.7

L-kynurenine + pyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoic acid + L-alanine

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2.6.1.7

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)2,4-dioxobutanoate + L-glutamate

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2.6.1.7

L-kynurenine + pyruvate = 4-(2-aminophenyl)2,4-dioxobutanoate + L-alanine

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2.6.1.7

14 entries

2.6.1.75

L-kynurenine + 2-oxoglutarate = L-glutamate + 4-(2-aminophenyl)-2,4-dioxobutanoate

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Enzyme Kinetic Parameters

References & Links

Literature References (2)

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Show Reference (2 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

394974

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D-Amino acid dehydrogenase (Pseudomonas fluorescens)

1971

Tsukada, K.

Methods Enzymol.

17B

623-624

636995

25837

Purification and characterization of aromatic-amino-acid-glyoxylate aminotransferase from monkey and rat liver

1978

Harada, I.; Noguchi, T.; Kido, R.

Hoppe-Seyler's Z. Physiol. Chem.

359

481-488

Links to other databases for 4-(2-aminophenyl)-2,4-dioxobutanoate

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Show Links (1 entry)

ChEBI

PubChem

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