print visible entries

print all entries

Ligand 4-(2-aminophenyl)-2,4-dioxobutanoic acid

Basic Ligand Information

Molecular Structure

Show all BRENDA pathways known for 4-(2-aminophenyl)-2,4-dioxobutanoic acid

close all tables

open all tables

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

top print hide

Show Natural Product (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.6.1.63

L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

0

-

2.6.1.7

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate + H2O

0

-

Product in Enzyme-catalyzed Reactions (25 results)

top print hide

Show Product (25 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.4.99.6

D-kynurenine + H2O + 2,6-dichlorophenolindophenol = 4-(2-aminophenyl)-2,4-dioxobutanoate + NH3 + reduced 2,6-dichlorophenolindophenol

394974

-

1.4.99.6

D-kynurenine + H2O + methylene blue = 4-(2-aminophenyl)-2,4-dioxobutanoate + NH3 + reduced methylene blue

394974

-

1.4.99.6

2 entries

2.6.1.44

kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

0

-

2.6.1.57

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate

0

-

2.6.1.63

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate

0

-

2.6.1.63

L-kynurenine + 4-methylsulfanyl-2-oxobutanoate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-methionine

0

-

2.6.1.63

L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

636995, 0

-

2.6.1.63

L-kynurenine + hydroxypyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-serine

0

-

2.6.1.63

L-kynurenine + pyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine

0

-

2.6.1.63

5 entries

2.6.1.64

L-kynurenine + pyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine

0

-

2.6.1.7

L-kynurenine + 2-oxobutanoate = 4-(2-aminophenyl)-2,4-dioxobutanoate + 2-aminobutanoate

0

-

2.6.1.7

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate

0

-

2.6.1.7

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate + H2O

0

-

2.6.1.7

L-kynurenine + 2-oxoisocaproate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-leucine

0

-

2.6.1.7

L-kynurenine + 2-oxoisocaproic acid = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-leucine

0

-

2.6.1.7

L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

0

-

2.6.1.7

L-kynurenine + mercaptopyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-cysteine

0

-

2.6.1.7

L-kynurenine + oxaloacetate = 4-(2-aminophenyl)-2,4-dioxobutanoate + 2-aminosuccinate

0

-

2.6.1.7

L-kynurenine + oxaloacetate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate

0

-

2.6.1.7

L-kynurenine + phenylpyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-phenylalanine

0, 636625

-

2.6.1.7

L-kynurenine + pyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine

0

-

2.6.1.7

L-kynurenine + pyruvate = 4-(2-aminophenyl)-2,4-dioxobutanoic acid + L-alanine

0

-

2.6.1.7

L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)2,4-dioxobutanoate + L-glutamate

0

-

2.6.1.7

L-kynurenine + pyruvate = 4-(2-aminophenyl)2,4-dioxobutanoate + L-alanine

0

-

2.6.1.7

14 entries

2.6.1.75

L-kynurenine + 2-oxoglutarate = L-glutamate + 4-(2-aminophenyl)-2,4-dioxobutanoate

0

-

Enzyme Kinetic Parameters

References & Links

Literature References (3)

top print hide

Show Reference (3 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

394974

-

D-Amino acid dehydrogenase (Pseudomonas fluorescens)

1971

Tsukada, K.

Methods Enzymol.

17B

623-624

636625

7493966

Cloning and functional expression of a soluble form of kynurenine/alpha-aminoadipate aminotransferase from rat kidney

1995

Buchli, R.; Alberati-Giani, D.; Malherbe, P.; Kohler, C.; Broger, C.; Cesura, A.M.

J. Biol. Chem.

270

29330-29335

636995

25837

Purification and characterization of aromatic-amino-acid-glyoxylate aminotransferase from monkey and rat liver

1978

Harada, I.; Noguchi, T.; Kido, R.

Hoppe-Seyler's Z. Physiol. Chem.

359

481-488

Links to other databases for 4-(2-aminophenyl)-2,4-dioxobutanoic acid

top print hide

Show Links (1 entry)

ChEBI

PubChem