Ligand 2-octenoyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of 2-octenoyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C29H48N7O17P3S
2-octenoyl-CoA
CPSDNAXXKWVYIY-NTLMCJQISA-N
Synonyms:
(2E)-oct-2-enoyl-CoA, (2E)-octenoyl-CoA, 2,3-trans-octenoyl-CoA, 2-trans-octenoyl-CoA, oct-2-enoyl-CoA, octa-2-enoyl-CoA, octenoyl-CoA, trans-2,3-octenoyl-CoA, trans-2-octenoyl-CoA, trans-oct-2-enoyl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
trans-2-octenoyl-CoA + NADPH + H+ = octanoyl-CoA + NADP+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
octanoyl-CoA + electron transferring flavoprotein = 2-octenoyl-CoA + reduced electron transferring flavoprotein
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
trans-2-octenoyl-CoA + NADH + H+ = octanoyl-CoA + NAD+
show the reaction diagram
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trans-2-octenoyl-CoA + NADH = octanoyl-CoA + NAD+
show the reaction diagram
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(2E)-oct-2-enoyl-CoA + NADPH + CO2 + H+ = (2S)-2-carboxyoctanoyl-CoA + NADP+
show the reaction diagram
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trans-2-octenoyl-CoA + H2O = (3S)-3-hydroxyoctanoyl-CoA
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (27 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
octanoyl-CoA + O2 = trans-2-octenoyl-CoA + H2O2
show the reaction diagram
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octanoyl-CoA + acceptor = oct-2-enoyl-CoA + reduced acceptor
show the reaction diagram
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octanoyl-CoA + electron-transfer flavoprotein = oct-2-enoyl-CoA + reduced electron-transfer flavoprotein + H+
show the reaction diagram
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acetyl-CoA + trans-2,3-octenoate = acetate + trans-2,3-octenoyl-CoA
show the reaction diagram
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(R)-3-hydroxyoctanoyl-CoA = octenoyl-CoA + H2O
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitively inhibits malonyl-transferase reaction
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (17 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.011
-
-
0.2327
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0.029
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pH 9.0

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0034
-
-
0.00028
-
pH 7.5, 25°C

References & Links

Links to other databases for 2-octenoyl-CoA

ChEBI
PubChem
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PubChem