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BRENDA support

Ligand phorbol 12,13-dibutanoate

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Basic Ligand Information

Molecular Structure
Picture of phorbol 12,13-dibutanoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C28H40O8
phorbol 12,13-dibutanoate
BQJRUJTZSGYBEZ-YVQNUNKESA-N
Synonyms:
phorbol-ester-12-13-dibutyrate, phorbol 12,13-dibutyrate, phorbol dibutyrate

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phorbol 12,13-dibutanoate + H2O = phorbol 13-butanoate + butanoate
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
stimulates activity on a posttranscriptional level
-
activates
-
induces an about 2fold maximum increase in caldesmon phosphorylation
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates Na+,K+-ATPase activity at low concentration, but inhibits it at high concentration, the inhibitory effect can be reversed by preincubation with ethoxyresorufin, 17-octadecynoic acid, wortmannin, LY294002, cytochlasin D, or latrunculin B

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

References & Links

Links to other databases for phorbol 12,13-dibutanoate

ChEBI
PubChem
ChEBI
PubChem