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Ligand O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 3 H2 6 NO7 PR2
O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine
1-alkyl-2-acylglycerophosphoethanolamine, 1-organyl-2-acyl-sn-glycero-3-phosphoethanolamine
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H2O
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + electron donor + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + oxidized electron donor + H2O
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Substrate in Enzyme-catalyzed Reactions (3 results)
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H2O
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + electron donor + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + oxidized electron donor + H2O
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + reduced cytochrome b5 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + oxidized cytochrome b5 + 2 H2O
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Enzyme Kinetic Parameters
References & Links Literature References (6)
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Enzymatic synthesis of plasmalogens. Characterization of the 1-O-alkyl-2-acyl-8n-glycero-3-phosphorylethanolamine desaturase from mucosa of hamster small intestine
1973
Paltauf, F.; Holasek, A.
J. Biol. Chem.
248
1609-1615
Evidence for a mixed function oxidase in the biosynthesis of ethanolamine plasmalogens from 1-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine
1972
Wykle, R.L.; Blank, M.L.; Malone, B.; Snyder, F.
J. Biol. Chem.
247
5442-5447
Formation of ether lipids and wax esters in mammalian cells. Specificity of enzymes with regard to carbon chains of substrates
1982
Weber, N.; Richter, J.
Biochim. Biophys. Acta
711
197-207
On the substrate specificity of enol ether formation in rat brain. Metabolism of O-alkyl ethanediol phosphorylethanolamine
1975
Baumann, W.J.; Madson, T.H.; Chang, N.; Bandi, P.C.; Schmidt, H.H.O.
Biochem. Biophys. Res. Commun.
66
717-724
Plasmanylethanolamine D1-desaturase
1992
Blank, M.L.; Snyder, F.
Methods Enzymol.
209
390-396
Orphan enzymes in ether lipid metabolism
2013
Watschinger, K.; Werner, E.R.
Biochimie
95
59-65
Links to other databases for O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine