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Ligand N2-(D-2-Carboxypropyl)-L-Arg

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

6.3.3.4

ATP + (2'S)-methyl-L-N2-(2-carboxyethyl)arginine = ?

728238

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Product in Enzyme-catalyzed Reactions (2 results)

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EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.5.1.11

L-Arg + 2-oxobutanoate + NADH = N2-(D-2-Carboxypropyl)-L-Arg + NAD+ + H2O

0

-

1.5.1.11

L-Arg + 2-oxobutanoate + NADPH = N2-(D-2-Carboxypropyl)-L-Arg + NADP+ + H2O

0

-

1.5.1.11

2 entries

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (4 results)

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EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

6.3.3.4

0.013

-

mutant enzyme H447A, pH and temperature not specified in the publication

728238

6.3.3.4

0.023

-

wild type enzyme, pH and temperature not specified in the publication

728238

6.3.3.4

0.13

-

mutant enzyme V446G, pH and temperature not specified in the publication

728238

6.3.3.4

0.34

-

mutant enzyme V446A, pH and temperature not specified in the publication

728238

6.3.3.4

4 entries

K_M Value (4 results)

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EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

6.3.3.4

0.06

-

wild type enzyme, pH and temperature not specified in the publication

728238

6.3.3.4

0.08

-

mutant enzyme H447A, pH and temperature not specified in the publication

728238

6.3.3.4

0.46

-

mutant enzyme V446A, pH and temperature not specified in the publication

728238

6.3.3.4

1.2

-

mutant enzyme V446G, pH and temperature not specified in the publication

728238

6.3.3.4

4 entries

References & Links

Literature References (1)

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BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

728238

23616913

Engineering the synthetic potential of beta-lactam synthetase and the importance of catalytic loop dynamics

2012

Labonte, J.W.; Kudo, F.; Freeman, M.F.; Raber, M.L.; Townsend, C.A.

MedChemComm

3

960-966

Links to other databases for N2-(D-2-Carboxypropyl)-L-Arg

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ChEBI

PubChem

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