Ligand L-azetidine-2-carboxylic acid

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Basic Ligand Information

Molecular Structure
Picture of L-azetidine-2-carboxylic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H7NO2
L-azetidine-2-carboxylic acid
IADUEWIQBXOCDZ-VKHMYHEASA-N
Synonyms:
L-2-acetidine-4-carboxylic acid, L-2-azetidinecarboxylic acid, L-Azetidine-2-carboxylate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + L-azetidine-2-carboxylic acid = CoA + N-acetyl-L-azetidine-2-carboxylic acid
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-2-azetidinecarboxylic acid + 2-oxoglutarate + O2 = cis-3-hydroxyazetidine-L-2-carboxylic acid + succinate + CO2
show the reaction diagram
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L-azetidine-2-carboxylate = D-azetidine-2-carboxylate
show the reaction diagram
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L-azetidine-2-carboxylate = D-azetidine-2-carboxylate
show the reaction diagram
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ATP + L-azetidine-2-carboxylate + L-threonine = ADP + phosphate + L-azetidine-2-carboxyl-L-threonine
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
50% inactivation at 2 mM
-
competitive
-
3 mM, 50% inhibition
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (17 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (21 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.1
-
-

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
20
-
-
0.3
-
wild type enzyme, at pH 7.5 and 30C

References & Links

Links to other databases for L-azetidine-2-carboxylic acid

ChEBI
PubChem
ChEBI
PubChem