Ligand D-ribulose 5-phosphate

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Basic Ligand Information

Molecular Structure
Picture of D-ribulose 5-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H11O8P
D-ribulose 5-phosphate
FNZLKVNUWIIPSJ-UHNVWZDZSA-N
Synonyms:
5-O-phosphono-D-ribulose, D-ribulose-5-phosphate, ribulose-5-phosphate, ribulose 5-phosphate
Pathway Source
Pathways


Show all pahtways known for Show all BRENDA pathways known for D-ribulose 5-phosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-tyrosine + D-ribulose 5-phosphate = (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H2O
show the reaction diagram
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L-tryptophan + D-ribulose 5-phosphate = (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H2O
show the reaction diagram
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D-Ribulose 5-phosphate = D-Xylulose 5-phosphate
show the reaction diagram

In Vivo Product in Enzyme-catalyzed Reactions (25 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+
show the reaction diagram
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6-phospho-D-gluconate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH + H+
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ATP + D-ribulose = ADP + D-ribulose 5-phosphate
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ATP + D-ribulose = ADP + D-ribulose 5-phosphate
show the reaction diagram
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D-arabino-hex-3-ulose 6-phosphate = D-ribulose 5-phosphate + formaldehyde
show the reaction diagram
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D-Arabinose 5-phosphate = D-Ribulose 5-phosphate
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Substrate in Enzyme-catalyzed Reactions (68 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-ribulose 5-phosphate + NADPH + H+ = D-ribitol 5-phosphate + NADP+
show the reaction diagram
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ribulose 5-phosphate + ribose 5-phosphate = a heptulose phosphate + glyceraldehyde 3-phosphate
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ribulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + 1,3-dihydroxyacetone
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phosphoenolpyruvate + D-ribulose 5-phosphate = ?
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ATP + ribulose-5-phosphate = AMP + 5-phospho-ribulose-1-diphosphate
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D-ribulose-5-phosphate + H2O = D-ribulose + phosphate
show the reaction diagram
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D-ribulose 5-phosphate + H2O = D-ribulose + phosphate
show the reaction diagram
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D-ribulose 5-phosphate + H2O = D-ribulose + phosphate
show the reaction diagram
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L-tyrosine + D-ribulose 5-phosphate = (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H2O
show the reaction diagram
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L-tryptophan + D-ribulose 5-phosphate = (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H2O
show the reaction diagram
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D-ribulose-5-phosphate = D-xylulose 5-phosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (41 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-ribitol 5-phosphate + NADP+ = D-ribulose 5-phosphate + NADPH + H+
show the reaction diagram
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hydroxypyruvate + D-glyceraldehyde 3-phosphate = CO2 + ribulose 5-phosphate
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ATP + D-ribulose = ADP + D-ribulose 5-phosphate
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ATP + D-ribulose = ADP + D-ribulose 5-phosphate
show the reaction diagram
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ATP + D-ribulose = ADP + D-ribulose 5-phosphate
show the reaction diagram
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ribulose 1,5-bisphosphate + H2O = ribulose 5-phosphate + phosphate
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D-arabino-hex-3-ulose 6-phosphate = D-ribulose 5-phosphate + formaldehyde
show the reaction diagram
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D-xylulose 5-phosphate = D-ribulose 5-phosphate
show the reaction diagram
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D-Arabinose 5-phosphate = D-Ribulose 5-phosphate
show the reaction diagram
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D-ribose 5-phosphate = D-ribulose 5-phosphate
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates
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activation
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Inhibitor in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
65% residual activity at 2 mM
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60% residual activity at 2 mM
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commercial D-ribulose 5-phosphate inhibits the enzyme
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3D Structure of Enzyme-Ligand-Complex (PDB) (49 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (29 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.18
-
in Tris-HCl 50 mM at pH 7.5, at 22C
58.8
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at pH 8.5 and 30C
0.0007
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pH 8.0, 37C, free pyridoxal 5'-phosphate synthase subunit (Pdx1)

KM Value (80 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.15
-
-
1.3
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in Tris-HCl 50 mM at pH 7.5, at 22C

References & Links

Links to other databases for D-ribulose 5-phosphate

ChEBI
PubChem
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PubChem