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Ligand D-2-Aminoadipic acid Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C6 H1 1 NO4
D-2-Aminoadipic acid
OYIFNHCXNCRBQI-SCSAIBSYSA-N
(R)-2-aminohexadioic acid, D-2-aminoadipate, D-alpha-aminoadipate, D-alpha-aminoadipic acid, D-aminoadipate
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
D-alpha-aminoadipate + H2O + O2 = 2-oxoadipate + NH3 + H2O2
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
L-2-aminoadipic acid = D-2-aminoadipic acid
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Substrate in Enzyme-catalyzed Reactions (4 results)
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D-2-aminoadipate + NADPH + H+ + ATP = (R)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
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D-alpha-aminoadipic acid + H2O + O2 = 2-oxoadipic acid + NH3 + H2O2
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D-aminoadipate + H2O + O2 = ?
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D-alpha-aminoadipate + H2O + O2 = 2-oxoadipate + NH3 + H2O2
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Product in Enzyme-catalyzed Reactions (2 results)
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cephalosporin C + H2O = 7-aminocephalosporanic acid + (R)-2-aminohexadioic acid
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L-2-aminoadipic acid = D-2-aminoadipic acid
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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KM Value (2 results)
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References & Links Literature References (6)
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Partial purification and specificity studies of the D-glutamate-adding and D-alanyl-D-alanine-adding enzymes from Escherichia coli K12
1987
Michaud, C.; Blanot, D.; Flouret, B.; van Heijenoort, J.
Eur. J. Biochem.
166
631-637
Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5
1999
Ehmann, D.E.; Gehring, A.M.; Walsh, C.T.
Biochemistry
38
6171-6177
Purification of beef kidney D-aspartate oxidase overexpressed in Escherichia coli and characterization of its redox potentials and oxidative activity towards agonists and antagonists of excitatory amino acid receptors
1999
Negri, A.; Tedeschi, G.; Ceciliani, F.; Ronchi, S.
Biochim. Biophys. Acta
1431
212-222
D-amino acid oxidase from the yeast Trigonopsis variabilis
1985
Kubicek-Pranz, E.M.; Röhr, M.
J. Appl. Biochem.
7
104-113
Distribution and characteristics of D-amino acid and D-aspartate oxidases in fish tissues
2003
Sarower, M.G.; Matsui, T.; Abe, H.
J. Exp. Zool. A
295
151-159
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Distribution and substrate specificity of D-amino acid and D-aspartate oxidases in marine invertebrates
2004
Sarower, M.G.; Matsui, T.; Abe, H.
Science Asia
30
335-340
Links to other databases for D-2-Aminoadipic acid
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