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Ligand apigenin 7-O-glucuronide Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C2 1 H1 8 O1 1
apigenin 7-O-glucuronide
JBFOLLJCGUCDQP-ZFORQUDYSA-N
apigenin-7-O-glucuronide, apigenin 7-O-beta-D-glucuronide, apigenin 7-O-beta-D-glucuronoside, apigenin beta-D-glucuronide
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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UDP-glucuronic acid + apigenin 7-O-beta-D-glucuronide = UDP + apigenin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]
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Product in Enzyme-catalyzed Reactions (4 results)
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UDP-D-glucuronate + apigenin = UDP + apigenin 7-O-beta-D-glucuronoside
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UDP-glucuronate + apigenin = UDP + apigenin beta-D-glucuronide
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UDPglucuronic acid + apigenin = UDP + apigenin 7-O-glucuronide
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apigenin 7,4'-diglucuronide + H2O = apigenin 7-O-glucuronide + glucuronic acid
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Activator in Enzyme-catalyzed Reactions (1 result)
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stimulates the enzyme and collagen biosynthesis in osteogenesis imperfecta type I cells, overview
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Enzyme Kinetic Parameters
References & Links Literature References (2)
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Three specific UDP-glucuronate: flavone-glucuronosyl-transferases from primary leaves of Secale cereale
1988
Schulz, M.; Weissenböck, G.
Phytochemistry
27
1261-1267
Stimulation of collagen biosynthesis by flavonoid glycosides in skin fibroblasts of osteogenesis imperfecta type I and the potential mechanism of their action
2007
Galicka, A.; Nazaruk, J.
Int. J. Mol. Med.
20
889-895
Links to other databases for apigenin 7-O-glucuronide