Ligand isofagomine

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Basic Ligand Information

Molecular Structure
Picture of isofagomine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H13NO3
isofagomine
QPYJXFZUIJOGNX-HSUXUTPPSA-N
Synonyms:
(3R,4R,5R)-3,4-dihydroxy-5-hydroxymethylpiperidine, (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol, D-isofagomine, fagomine

Roles as Enzyme Ligand

Product in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
stereoisomer of (-)-1-azafagomine, racemic, competitive
-

3D Structure of Enzyme-Ligand-Complex (PDB) (72 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0058
-
pH 6.8, 25°C
0.0000084
0.000025
pH and temperature not specified in the publication
0.14
-
pH 6.8, 37°C

IC50 Value (12 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for isofagomine

ChEBI
PubChem
-
PubChem