Ligand 5,6,7,8-Tetrahydropteroate
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Basic Ligand Information
Molecular Structure

C14H16N6O3
5,6,7,8-Tetrahydropteroate
OXIZGFYJYJOABB-VIFPVBQESA-M
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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tetrahydropteroic acid + N-formimino-L-glutamate = 5-formiminotetrahydropteroic acid + L-glutamate
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ATP + 5,6,7,8-tetrahydropteroate + Glu = ADP + phosphate + 5,6,7,8-terahydropteroyl-Glu
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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5,6,7,8-tetrahydropteroyl-Glu2 formation
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Enzyme Kinetic Parameters
KM Value (1 result)
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References & Links
Literature References (4)
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Corynebacterium species folylpoly-gamma-glutamate synthetase
1982
Shane, B.
Pept. Antibiot. Biosynth. Funct. (Kleinkauf H. et al. eds. )
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353-368
Folylpoly-gamma-glutamate synthesis by bacteria and mammalian cells
1981
Cichowicz, D.J.; Foo, S.K.; Shane, B.
Mol. Cell. Biochem.
39
209-228
Pteroylpoly(gamma-glutamate) synthesis by Corynebacterium species. Purification and properties of folylpoly(gamma-glutamate) synthetase
1980
Shane, B.
J. Biol. Chem.
255
5655-5662
Kinetic mechanism of formininotransferase from porcine liver
1975
Beaudet, R.; Mackenzie, R.
Biochim. Biophys. Acta
410
252-261
Links to other databases for 5,6,7,8-Tetrahydropteroate