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Ligand 3-Chloropropanoate

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.8.1.3

3-chloropropionate + H2O = 3-hydroxypropionate + chloride

719141

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Substrate in Enzyme-catalyzed Reactions (5 results)

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Show Substrate (5 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.8.3.1

acetyl-CoA + chloropropionate = acetate + chloropropionyl-CoA

737535

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3.8.1.3

3-chloropropionate + H2O = 3-hydroxypropionate + chloride

719141

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3.8.1.9

3-chloropropionate + H2O = 3-hydroxypropionate + chloride

733552, 733999

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6.2.1.1

ATP + 3-chloropropanoate + CoA = AMP + diphosphate + 3-chloropropanoyl-CoA

550

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6.2.1.36

3-chloropropionate + ATP + coenzyme A = 3-chloropropionyl-CoA + AMP + diphosphate

692841

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Product in Enzyme-catalyzed Reactions (1 result)

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Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.5.5.7

3-chloropropionitrile + H2O = 3-chloropropanoate + NH3

0

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Activator in Enzyme-catalyzed Reactions (1 result)

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Show Activating Compound (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.11.1.18

acts as a cofactor

764075

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Enzyme Kinetic Parameters

References & Links

Literature References (7)

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Show Reference (7 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

550

2884217

Substrate specificity of acetyl coenzyme A synthetase

1987

Patel, S.S.; Walt, D.R.

J. Biol. Chem.

262

7132-7134

692841

18165310

3-Hydroxypropionyl-coenzyme A synthetase from Metallosphaera sedula, an enzyme involved in autotrophic CO2 fixation

2008

Alber, B.E.; Kung, J.W.; Fuchs, G.

J. Bacteriol.

190

1383-1389

719141

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Enhancement of haloacetate dehalogenase production by strain mutation and condition optimization

2011

Lin, C.; Yang, L.; Xu, G.; Wu, J.

Biotechnol. Bioprocess Eng.

16

923-929

733552

26019583

Interactions of non-natural halogenated substrates with D-specific dehalogenase (DehD) mutants using in silico studies

2014

Sudi, I.Y.; Shamsir, M.S.; Jamaluddin, H.; Wahab, R.A.; Huyop, F.

Biotechnol. Biotechnol. Equip.

28

949-957

733999

23443090

Structure prediction, molecular dynamics simulation and docking studies of D-specific dehalogenase from Rhizobium sp. RC1

2012

Sudi, I.Y.; Wong, E.L.; Joyce-Tan, K.H.; Shamsir, M.S.; Jamaluddin, H.; Huyop, F.

Int. J. Mol. Sci.

13

15724-15754

737535

24057402

Characterization of propionate CoA-transferase from Ralstonia eutropha H16

2014

Volodina, E.; Schuermann, M.; Lindenkamp, N.; Steinbuechel, A.

Appl. Microbiol. Biotechnol.

98

3579-3589

764075

31204052

A useful propionate cofactor enhancing activity for organic solvent-tolerant recombinant metal-free bromoperoxidase (perhydrolase) from Streptomyces aureofaciens

2019

China, H.; Ogino, H.

Biochem. Biophys. Res. Commun.

516

327-332

Links to other databases for 3-Chloropropanoate

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Show Links (1 entry)

ChEBI

PubChem

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