Ligand 3,12-Dioxo-5beta-cholanoate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of 3,12-Dioxo-5beta-cholanoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C24H36O4
3,12-Dioxo-5beta-cholanoate
XNTYYYINMGRBQW-ZEZONBOOSA-N
Synonyms:
3,12-Diketolithocholic acid, 3,12-dioxo-5-beta-cholan-24-oic acid, 3,12-dioxo-5beta-cholan-24-oic acid, 3,12-dioxo-5beta-cholanate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3,12-dioxo-5-beta-cholan-24-oic acid + NADH + H+ = 3beta-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD+
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3,12-dioxo-5beta-cholanoate + NADPH = 12beta-hydroxy-3-oxo-5beta-cholanoate + NADP+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dehydrocholic acid + NADH = 3,12-diketolithocholic acid + NAD+
show the reaction diagram
-

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0895
-
-

References & Links

Links to other databases for 3,12-Dioxo-5beta-cholanoate

ChEBI
PubChem
-
PubChem