Ligand beta-endorphin

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Basic Ligand Information

Molecular Structure
Picture of beta-endorphin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C149H242N38O44S
beta-endorphin
FKKMLNBKPJXIIJ-NOSLXCIXSA-N
Synonyms:
betaendorphin, beta endorphin

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
beta-endorphin + H2O = ?
show the reaction diagram
-
beta-endorphin + H2O = ?
show the reaction diagram
-
beta-endorphin + H2O = Met-enkephalin + ?
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
beta-endorphin + H2O = ?
show the reaction diagram
-
beta-endorphin + H2O = Met-enkephalin + ?
show the reaction diagram
-
beta-endorphin + H2O = fragments of beta-endorphin
show the reaction diagram
-
beta-endorphin + H2O = ?
show the reaction diagram
-
beta-endorphin + H2O = ?
show the reaction diagram
-
beta-endorphin + H2O = Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe + Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Gln + ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
POMC prohormone precursor + H2O = ACTH + alpha-MSH + beta-endorphin
show the reaction diagram
-
-
Pro-opiomelanocortin + H2O = Adrenocorticotropic hormone + beta-lipotropin + beta endorphin
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
opioid receptor-mediated activation
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibitor
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
26
-
-
12.5
-
pH 8.0, 37°C

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.00654
-
-
0.00036
-
pH 8.0, 37°C
0.0014
-
pH 7.0, 37°C

References & Links

Links to other databases for beta-endorphin

ChEBI
PubChem
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PubChem